Fixolin Tablet 200 mg contains Doxophylline, a modern bronchodilator from the methylxanthine group, used in the treatment and long-term management of respiratory diseases characterized by airway obstruction. It is commonly prescribed for patients with bronchial asthma and chronic obstructive pulmonary disease to relieve bronchospasm, improve breathing, and enhance overall respiratory comfort.

Doxophylline offers effective bronchodilation with a better safety and tolerability profile compared to traditional xanthines such as theophylline. Its selective mechanism reduces the risk of cardiovascular and central nervous system side effects, making Fixolin Tablet suitable for prolonged therapy under medical supervision.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Fixolin Tablet 200 mg is indicated for:

• Bronchial asthma

• Chronic obstructive pulmonary disease

• Chronic bronchitis

• Emphysema

• Other respiratory conditions associated with bronchospasm

Pharmacological Action

Doxophylline works by inhibiting phosphodiesterase enzymes, leading to increased intracellular cyclic AMP levels in bronchial smooth muscle. This results in relaxation of the airway muscles and sustained bronchodilation. It also improves diaphragmatic contractility and exhibits mild anti-inflammatory activity. Unlike theophylline, Doxophylline has minimal affinity for adenosine receptors, which helps reduce cardiac stimulation and central nervous system effects.

Dosage and Administration

• Dosage is individualized based on disease severity and patient response.

• Fixolin Tablet is administered orally and can be taken with or without food.

• Patients should follow the prescribed dosing schedule and avoid self-adjustment of dose.

• Long-term use requires periodic medical evaluation.

Benefits

• Effective relief from bronchospasm

• Suitable for maintenance therapy in asthma and COPD

• Better tolerability compared to traditional xanthines

• Reduced risk of cardiac and CNS adverse effects

• Convenient oral tablet formulation

Side Effects

Common side effects may include:

• Nausea

• Vomiting

• Headache

• Gastric discomfort

• Mild dizziness

These side effects are usually mild and transient when used at recommended doses.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions and Warnings

• Use with caution in patients with cardiovascular disease, liver impairment, or peptic ulcer

• Not recommended during pregnancy and breastfeeding unless clearly necessary

• Avoid excessive intake of caffeine-containing products

• Regular follow-up is advised during prolonged therapy

Drug Interactions

Doxophylline may interact with certain antibiotics, anticonvulsants, and other bronchodilators. Patients should inform their healthcare provider about all medications they are taking.

Storage

Store below 30°C in a cool, dry place. Protect from light and moisture. Keep out of reach of children.

Fixolin Tablet 200 mg provides effective and well-tolerated bronchodilator therapy, helping patients with chronic respiratory conditions breathe more easily and maintain better control of their symptoms.