Finacof Syrup is a combination syrup containing Phenylephrine 5 mg and Promethazine 6.25 mg per 5 ml, formulated to provide rapid relief from symptoms of allergic conditions, nasal congestion, and upper respiratory tract discomfort. This dual-action syrup works both as a decongestant and an antihistamine, offering effective symptomatic relief from runny nose, sneezing, nasal congestion, itching, and watery eyes commonly associated with colds, hay fever, and allergic rhinitis.

Phenylephrine acts as a selective alpha-1 adrenergic receptor agonist, constricting nasal blood vessels to reduce swelling and congestion. Promethazine, a first-generation antihistamine, blocks H1 receptors, alleviating allergic reactions, pruritus, and sneezing. The syrup’s palatable formulation ensures easy administration, making it suitable for adults and children above the recommended age. Finacof Syrup provides both immediate relief from nasal and eye symptoms and helps improve overall comfort during allergic episodes.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Phenylephrine Hydrochloride: 5 mg

• Promethazine Hydrochloride: 6.25 mg

• Dosage Form: Syrup

• Route of Administration: Oral

Therapeutic Class

• Sympathomimetic decongestants

• Antihistamines (H1 receptor antagonists)

• Combination therapy for allergy and cold symptoms

Indications

Finacof Syrup is indicated for the symptomatic relief of:

• Allergic rhinitis: Sneezing, nasal congestion, runny nose, and itchy, watery eyes

• Common cold symptoms: Nasal congestion, mild cough, and postnasal drip

• Hay fever: Seasonal allergy symptoms

• Other allergic conditions: Pruritus and urticaria-related discomfort

It is suitable for short-term use to manage acute symptoms and improve patient comfort.

Pharmacology

• Phenylephrine acts on alpha-1 adrenergic receptors in the nasal mucosa, causing vasoconstriction. This reduces nasal swelling and congestion, facilitating easier breathing.

• Promethazine competitively blocks histamine at H1 receptors, preventing histamine-mediated allergy symptoms such as sneezing, itching, and watery eyes. It also has mild sedative properties, helping relieve associated discomfort and restlessness.

• The combination of phenylephrine and promethazine provides a synergistic effect, addressing both the cause and symptoms of allergic reactions and congestion efficiently.

Dosage and Administration

• Adults and children over 12 years: 5–10 ml, 3 times daily, or as directed by a physician

• Children 6–12 years: 2.5–5 ml, 3 times daily

• Shake well before use

• Administer using a calibrated measuring spoon or cup

• Use the lowest effective dose for the shortest duration necessary

Note: Dosage should be individualized based on age, weight, and clinical condition.

Contraindications

• Hypersensitivity to phenylephrine, promethazine, or any component of the syrup

• Patients with severe hypertension, coronary artery disease, or cardiac arrhythmias

• Children under 2 years of age

• Patients with glaucoma, urinary retention, or severe respiratory conditions

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions and Warnings

• Use with caution in patients with hypertension, diabetes, thyroid disorders, or cardiovascular disease

• Avoid concurrent use with monoamine oxidase inhibitors (MAOIs) or other sympathomimetics

• May cause drowsiness; avoid driving or operating machinery if affected

• Do not exceed recommended dose to prevent cardiovascular or CNS side effects

Side Effects

Common side effects may include:

• Drowsiness or sedation

• Dizziness or lightheadedness

• Nausea or gastrointestinal discomfort

• Dry mouth or throat

• Rare: Palpitations, tremors, restlessness, or allergic reactions

Use in Pregnancy and Lactation

• Promethazine is categorized as Pregnancy Category C; use only if clearly indicated

• Phenylephrine should be used cautiously during pregnancy

• Avoid use while breastfeeding unless benefits outweigh risks

Storage Conditions

• Store below 30°C in a dry place

• Protect from light and moisture

• Keep out of reach of children

• Shake well before use.