Famiclav Tablet 500 mg + 125 mg is a powerful combination antibiotic containing Cefuroxime Axetil, a second-generation cephalosporin, and Clavulanic Acid, a beta-lactamase inhibitor. This formulation is designed to enhance antibacterial efficacy by overcoming resistance mechanisms and providing broad-spectrum coverage against a wide range of susceptible and beta-lactamase-producing bacteria.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Cefuroxime Axetil: 500 mg

• Clavulanic Acid: 125 mg

Pharmacological Action

Cefuroxime Axetil is an orally administered prodrug that is converted into its active form, cefuroxime, after absorption. Cefuroxime inhibits bacterial cell wall synthesis, resulting in bacterial cell death. Clavulanic Acid protects cefuroxime from degradation by beta-lactamase enzymes produced by resistant bacteria. The combination significantly broadens the antibacterial spectrum and improves treatment outcomes.

Indications

Famiclav Tablet 500 mg + 125 mg is indicated for the treatment of moderate to severe bacterial infections caused by susceptible and resistant organisms, including:

• Upper and lower respiratory tract infections such as sinusitis, bronchitis, and pneumonia

• Ear, nose, and throat infections including tonsillitis, pharyngitis, and otitis media

• Urinary tract infections

• Skin and soft tissue infections

• Dental infections

• Other community-acquired bacterial infections as prescribed by a physician

Dosage and Administration

• Adults: One tablet twice daily, or as directed by a healthcare professional

• Tablets should be taken after meals to enhance absorption and minimize gastrointestinal side effects

The full course of treatment should be completed as prescribed, even if symptoms improve earlier, to reduce the risk of antibiotic resistance.

Benefits and Advantages

• Broad-spectrum antibacterial coverage

• Effective against beta-lactamase-producing organisms

• Enhanced efficacy compared to single-antibiotic therapy

• Suitable for moderate to severe infections

• Convenient oral tablet form supports patient adherence

Safety and Precautions

Famiclav Tablet is generally well tolerated when used appropriately. Common side effects may include nausea, diarrhea, vomiting, abdominal discomfort, headache, or mild skin reactions. These effects are usually transient.

• Contraindicated in patients with known hypersensitivity to cephalosporins, clavulanic acid, or other beta-lactam antibiotics

• Use with caution in patients with a history of severe penicillin allergy

• Prolonged use may lead to superinfection with non-susceptible organisms

• Use during pregnancy and breastfeeding only when clearly indicated by a physician

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Drug Interactions

Antacids and acid-suppressing agents may reduce the absorption of Cefuroxime Axetil. An appropriate dosing interval should be maintained if these medications are used concurrently.

Storage

• Store below 30°C

• Protect from light and moisture

• Keep out of reach of children

• Do not use after the expiry date

Pack Information

Famiclav Tablet 500 mg + 125 mg is supplied in blister packs to ensure product stability, accurate dosing, and patient convenience.