Eronib Tablet 150 mg contains Erlotinib, a targeted anticancer medicine used in the treatment of certain types of non-small cell lung cancer (NSCLC) and pancreatic cancer. It belongs to a class of medicines known as tyrosine kinase inhibitors (TKIs), which work by blocking specific proteins involved in cancer cell growth and spread.

Erlotinib specifically targets the epidermal growth factor receptor (EGFR), a protein found on the surface of some cancer cells. In many cancers, particularly certain types of lung cancer, EGFR is overactive or mutated, leading to uncontrolled cell division. By inhibiting EGFR activity, Eronib Tablet helps slow down or stop the growth of cancer cells and may reduce tumor progression.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Eronib Tablet 150 mg is indicated for:

• First-line treatment of metastatic non-small cell lung cancer (NSCLC) with EGFR mutations

• Maintenance therapy in patients with advanced NSCLC

• Treatment of locally advanced or metastatic NSCLC after failure of at least one prior chemotherapy regimen

• In combination with gemcitabine for the treatment of metastatic pancreatic cancer

Treatment should be initiated and monitored by an experienced oncologist.

Mechanism of Action

Erlotinib works by selectively inhibiting the tyrosine kinase activity of the EGFR. This receptor is responsible for transmitting signals that promote cell growth and survival. When EGFR is blocked, cancer cells are unable to receive growth signals, leading to reduced proliferation and increased apoptosis (programmed cell death). This targeted approach allows for more specific cancer treatment compared to traditional chemotherapy.

Dosage and Administration

• The recommended dose is one 150 mg tablet taken once daily.

• It should be taken on an empty stomach, at least 1 hour before or 2 hours after food.

• The tablet should be swallowed whole with water and not crushed or chewed.

• Dose adjustments may be necessary based on tolerance, side effects, or liver function.

Regular follow-up and laboratory monitoring are essential during treatment.

Precautions and Warnings

• Use with caution in patients with liver impairment.

• Interstitial lung disease-like events have been reported; any new or worsening respiratory symptoms should be evaluated immediately.

• Severe skin reactions and diarrhea may occur and require dose modification.

• Avoid smoking, as it may reduce the effectiveness of Erlotinib.

• Women of childbearing potential should use effective contraception during treatment.

Possible Side Effects

Common side effects include:

• Skin rash

• Diarrhea

• Loss of appetite

• Fatigue

• Nausea and vomiting

Serious adverse effects may include severe lung problems, liver toxicity, gastrointestinal perforation, and severe skin reactions. Immediate medical attention is necessary if severe symptoms develop.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Storage Instructions

• Store below 30°C in a dry place.

• Keep away from moisture and direct sunlight.

• Keep out of reach of children.

Eronib Tablet 150 mg offers a targeted and effective treatment option for patients with specific types of lung and pancreatic cancers. When used under proper medical supervision, it helps control disease progression and improve treatment outcomes.