Eptase Injection contains Streptokinase 1.5 million IU, a thrombolytic (clot-busting) medicine used to dissolve abnormal blood clots in the blood vessels. It is primarily used in emergency conditions such as acute myocardial infarction (heart attack), pulmonary embolism, and other life-threatening thromboembolic disorders. Streptokinase works by restoring blood flow to the affected area, thereby reducing tissue damage and improving survival outcomes.

This injection is administered only in hospital settings under strict medical supervision due to the high risk of bleeding and the need for emergency monitoring.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Therapeutic Uses

Eptase Injection is indicated for:

• Acute myocardial infarction (heart attack)
• Pulmonary embolism (blood clot in lungs)
• Deep vein thrombosis (in selected cases)
• Arterial thromboembolism
• Thrombosis in vascular catheters (as advised)
• Other life-threatening clot-related emergencies

It is most effective when given early in acute cardiac events.

Mechanism of Action

Streptokinase works as a fibrinolytic agent by:

• Activating plasminogen to form plasmin
• Breaking down fibrin, the main component of blood clots
• Dissolving existing clots in blood vessels
• Restoring blood flow to affected tissues
• Reducing damage caused by oxygen deprivation

This helps reopen blocked arteries and improves oxygen supply to vital organs.

Dosage & Administration

• Administered as intravenous infusion only
• Dose and duration are determined by emergency clinical protocols
• Given under continuous monitoring of vital signs
• Should be used as early as possible after symptom onset (especially in heart attack cases)
• Must only be administered in ICU or emergency care settings
• Strict observation for bleeding complications is required

Self-administration is strictly prohibited.

Side Effects

Eptase Injection may cause serious side effects, including:

• Bleeding (internal or external)
• Hypotension (low blood pressure)
• Allergic reactions or fever
• Nausea and vomiting
• Arrhythmias (especially during myocardial infarction treatment)
• Injection-related reactions
• Rare severe hemorrhagic complications

Immediate medical attention is required if abnormal bleeding occurs.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions

• Contraindicated in active bleeding disorders
• Not suitable for recent surgery or major trauma patients
• Avoid in patients with history of hemorrhagic stroke
• Use with extreme caution in hypertension
• Careful monitoring of coagulation parameters is essential
• Only trained healthcare professionals should administer
• Risk-benefit assessment is mandatory before use

Storage

• Store below 25°C in a cool and dry place
• Protect from light
• Do not freeze
• Use immediately after reconstitution
• Keep out of reach of children
• Do not use after expiry date.