Enoparin Injection 8000 Anti-Xa IU/0.8 ml contains Enoxaparin Sodium, a low molecular weight heparin (LMWH) used as an anticoagulant to prevent and treat blood clot formation. It works by inhibiting key clotting factors in the blood, reducing the risk of deep vein thrombosis (DVT), pulmonary embolism (PE), and other thromboembolic disorders. This higher-strength formulation is used in patients requiring more intensive anticoagulant therapy under strict medical supervision.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

Each prefilled syringe (0.8 ml) contains:

• Enoxaparin Sodium 8000 Anti-Xa IU

This provides a reliable and predictable anticoagulant effect for high-risk patients.

Indications

Enoparin Injection is indicated for:

• Prevention of deep vein thrombosis (DVT) in high-risk surgical and medical patients
• Treatment of DVT and pulmonary embolism
• Acute coronary syndrome (unstable angina and non-ST elevation myocardial infarction)
• Thromboprophylaxis in immobilized or critically ill patients
• Prevention of clotting in selected clinical conditions

It should be used only under hospital supervision.

Pharmacological Action

Enoxaparin enhances the activity of antithrombin III:

• Primarily inhibits Factor Xa, reducing thrombin generation
• Minimally affects Factor IIa (thrombin)
• Prevents fibrin clot formation and propagation
• Provides a more predictable anticoagulant response than unfractionated heparin

This mechanism helps reduce the risk of life-threatening thromboembolic events.

Dosage & Administration

• Administered by subcutaneous injection only unless otherwise directed
• Dose depends on patient condition, weight, and renal function
• Commonly given once or twice daily as prescribed by a physician
• Injection sites should be rotated to minimize local irritation

Must be administered by a healthcare professional or trained caregiver.

Side Effects

Possible side effects include:

• Bleeding (most important risk)
• Bruising or pain at injection site
• Thrombocytopenia (low platelet count)
• Anemia
• Allergic reactions (rare)

Seek immediate medical attention if signs of abnormal bleeding occur.

Contraindications

• Active major bleeding
• History of heparin-induced thrombocytopenia (HIT)
• Severe thrombocytopenia
• Hypersensitivity to Enoxaparin or heparin products

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions & Warnings

• Use cautiously in renal impairment
• Regular monitoring of platelet counts is recommended
• Increased bleeding risk with other anticoagulants or NSAIDs
• Do not administer intramuscularly
• Dose adjustment may be required in elderly or low body weight patients

Use in Pregnancy & Lactation

Enoxaparin is considered safe in pregnancy when clinically indicated, as it does not cross the placenta. It should be used only under strict medical supervision.

Storage

• Store below 25°C
• Do not freeze
• Keep in original packaging
• Keep out of reach of children.