Empaglif-M Tablet 12.5 mg + 500 mg contains Empagliflozin 12.5 mg and Metformin Hydrochloride 500 mg, a combination oral antidiabetic medicine used to improve blood sugar control in adults with type 2 diabetes mellitus. This dual-action therapy combines an SGLT2 (Sodium-Glucose Co-Transporter 2) inhibitor with a biguanide, providing effective glycemic control through complementary mechanisms.

Empagliflozin lowers blood glucose by helping the kidneys remove excess sugar through the urine, while Metformin decreases glucose production in the liver, reduces intestinal glucose absorption, and improves the body's sensitivity to insulin. Together, these medicines help achieve better blood sugar control than either medicine alone.

In addition to lowering blood glucose and HbA1c levels, Empagliflozin provides proven cardiovascular and kidney benefits in eligible patients. The combination may also contribute to modest weight loss and blood pressure reduction when used alongside a healthy diet and regular physical activity.

Empaglif-M Tablet is intended for long-term management of type 2 diabetes and should be used under the supervision of a qualified healthcare professional.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

Each tablet contains:

• Empagliflozin 12.5 mg
• Metformin Hydrochloride 500 mg

How Empaglif-M Tablet Works

Empaglif-M Tablet combines two medicines with different but complementary mechanisms of action:

• Empagliflozin blocks the SGLT2 proteins in the kidneys, reducing glucose reabsorption and increasing glucose excretion through the urine.
• Metformin Hydrochloride reduces glucose production by the liver, decreases glucose absorption from the intestine, and improves insulin sensitivity, enabling the body to use insulin more effectively.

Together, these actions help lower fasting and post-meal blood sugar levels while reducing the risk of long-term diabetes-related complications.

Indications

Empaglif-M Tablet is indicated for:

• Type 2 diabetes mellitus in adults
• Improvement of glycemic control when diet and exercise alone are insufficient
• Patients requiring combination therapy with Empagliflozin and Metformin
• Reduction of cardiovascular risk in eligible patients with type 2 diabetes and established cardiovascular disease
• Appropriate patients with heart failure or chronic kidney disease, as determined by a healthcare provider

Note: Empaglif-M Tablet is not indicated for the treatment of type 1 diabetes mellitus or diabetic ketoacidosis.

Benefits of Empaglif-M Tablet

• Effectively lowers blood glucose and HbA1c levels
• Combines two complementary antidiabetic medicines in one tablet
• Improves insulin sensitivity
• Helps reduce excess glucose through the urine
• Supports heart and kidney health in eligible patients
• May promote modest weight loss
• May help lower blood pressure
• Convenient oral combination therapy that may reduce pill burden

Dosage and Administration

Take Empaglif-M Tablet exactly as prescribed by your healthcare provider.

• Take the tablet with meals to reduce the likelihood of stomach upset associated with Metformin.
• Swallow the tablet whole with a glass of water.
• Take it at the same time each day.
• Maintain adequate hydration during treatment.
• Continue following your recommended diet, exercise plan, and blood glucose monitoring schedule.

Do not stop taking the medicine without consulting your healthcare provider.

Possible Side Effects

Like all medicines, Empaglif-M Tablet may cause side effects, although not everyone experiences them.

Common side effects include:

• Nausea
• Diarrhea
• Abdominal discomfort
• Increased urination
• Urinary tract infection
• Genital yeast infections
• Headache
• Dizziness

Rare but serious side effects may include:

• Lactic acidosis (associated with Metformin)
• Diabetic ketoacidosis
• Kidney function impairment
• Severe dehydration
• Serious allergic reactions

Seek immediate medical attention if you experience persistent vomiting, severe weakness, difficulty breathing, severe abdominal pain, confusion, or signs of a serious infection.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions

Before taking Empaglif-M Tablet, inform your healthcare provider if you:

• Have kidney or liver disease
• Have heart failure or severe dehydration
• Have a history of diabetic ketoacidosis
• Consume excessive alcohol
• Have recurrent urinary tract or genital infections
• Are scheduled for surgery or imaging procedures requiring iodinated contrast media
• Are pregnant, planning to become pregnant, or breastfeeding
• Are taking insulin, sulfonylureas, diuretics, or other medicines that may interact with this combination

Regular monitoring of blood glucose, kidney function, vitamin B12 levels (during long-term Metformin therapy), and overall health is recommended.

Storage

• Store below 30°C in a cool and dry place.
• Protect from moisture and direct sunlight.
• Keep the tablets in their original packaging.
• Keep out of the reach of children.
• Do not use after the expiry date printed on the package.