Elacentra Tablet contains Elacestrant 345 mg, an oral selective estrogen receptor degrader (SERD) used in the treatment of hormone receptor-positive (HR+), HER2-negative advanced or metastatic breast cancer. It is specifically indicated for patients whose disease has progressed following prior endocrine therapy. Elacestrant provides a targeted hormonal treatment option that works by directly acting on estrogen receptors involved in tumor growth.

This medicine is administered orally and is used under strict supervision of an oncology specialist as part of a comprehensive cancer management plan.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Therapeutic Uses

Elacentra Tablet is indicated for:

• HR-positive, HER2-negative advanced or metastatic breast cancer
• Patients with progression after endocrine-based therapies
• Endocrine-resistant breast cancer (as determined by oncologist)
• Cases involving ESR1 mutation-positive tumors (based on testing)
• Long-term hormonal therapy in selected patients

Treatment is individualized based on disease stage, prior therapies, and molecular profiling.

Mechanism of Action

Elacestrant is a selective estrogen receptor degrader (SERD) that works by:

• Binding to estrogen receptors in breast cancer cells
• Blocking estrogen-driven signaling pathways
• Promoting degradation of estrogen receptors
• Reducing cancer cell growth and survival
• Helping overcome resistance to previous hormone therapies

By targeting the estrogen receptor pathway, it helps slow or control tumor progression in hormone-sensitive cancers.

Dosage & Administration

• Recommended dose: as prescribed by an oncologist (commonly once daily oral dose)
• Should be taken at the same time each day
• May be taken with or without food
• Swallow whole with water; do not crush or chew
• Treatment duration depends on clinical response and tolerance
• Regular follow-up and laboratory monitoring are required

Strict adherence to prescribed dosing is essential for effectiveness and safety.

Side Effects

Common side effects may include:

• Nausea and vomiting
• Fatigue or weakness
• Decreased appetite
• Hot flashes
• Muscle or joint pain
• Constipation or diarrhea
• Increased cholesterol levels
• Elevated liver enzymes

Patients should be monitored regularly, and supportive care may be provided to manage symptoms.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions

• Use only under oncology specialist supervision
• Not recommended during pregnancy or breastfeeding
• Liver function monitoring may be required
• Caution in patients with hepatic impairment
• Inform physician about all current medications to avoid interactions
• Effective contraception should be used during treatment and after discontinuation as advised

Storage

• Store below 25°C in a cool, dry place
• Protect from light and moisture
• Keep in original packaging
• Do not freeze
• Keep out of reach of children.