Glycenor M ER Tablet is a combination of Empagliflozin and Metformin Hydrochloride (Extended Release) used for the management of type 2 diabetes mellitus. This dual-action formulation helps improve glycemic control through complementary mechanisms, reducing both hepatic glucose production and renal glucose reabsorption. The extended-release (ER) form of Metformin provides better gastrointestinal tolerance and sustained blood glucose control.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

Each extended-release tablet contains:

• Empagliflozin 5 mg
• Metformin Hydrochloride 1000 mg (ER)

This combination is designed for effective and long-lasting control of blood sugar levels in adult diabetic patients.

Indications

Glycenor M ER Tablet is indicated for:

• Type 2 diabetes mellitus
• Patients inadequately controlled on monotherapy or other combinations
• Adjunct to diet and exercise for better glycemic control
• Reduction of cardiovascular risk in appropriate patients (as advised by physician)

Pharmacological Action

This combination works through dual complementary mechanisms:

• Empagliflozin: Inhibits SGLT2 in the kidneys, increasing urinary glucose excretion and lowering blood glucose independently of insulin
• Metformin (ER): Reduces hepatic glucose production, decreases intestinal glucose absorption, and improves insulin sensitivity with prolonged release for sustained effect

Together, they provide improved fasting and postprandial glucose control with metabolic benefits.

Dosage & Administration

• Dosage is individualized based on patient condition and physician guidance
• Commonly taken once or twice daily with meals
• Swallow tablet whole; do not crush or chew extended-release formulation
• Maintain adequate hydration during therapy
• Regular blood glucose monitoring is recommended

Side Effects

Possible side effects include:

• Nausea or vomiting
• Diarrhea or abdominal discomfort
• Increased urination
• Genital or urinary tract infections
• Hypoglycemia (when combined with insulin or sulfonylureas)
• Rare risk of lactic acidosis (due to metformin)

Contraindications

• Type 1 diabetes mellitus
• Diabetic ketoacidosis
• Severe renal impairment
• Metabolic acidosis
• Hypersensitivity to Empagliflozin or Metformin

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions & Warnings

• Monitor renal function before and during treatment
• Risk of dehydration due to osmotic diuresis
• Lactic acidosis risk in renal, hepatic, or severe illness conditions
• Use cautiously in elderly patients
• Temporary discontinuation may be required during surgery or acute illness

Use in Pregnancy & Lactation

This combination is not recommended during pregnancy or breastfeeding. Insulin is preferred for diabetes management during pregnancy.

Storage

• Store below 30°C
• Protect from moisture and heat
• Keep in original packaging
• Keep out of reach of children.