Dexoprex Capsule 60 mg contains Dexlansoprazole, a proton pump inhibitor (PPI) used for the treatment of acid-related gastrointestinal disorders. It is commonly prescribed for gastroesophageal reflux disease (GERD), erosive esophagitis, and other conditions caused by excess stomach acid. Dexlansoprazole has a dual delayed-release formulation, providing prolonged acid suppression and improved symptom control throughout the day and night.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

Each capsule contains:

• Dexlansoprazole 60 mg

Mechanism of Action

Dexlansoprazole inhibits the hydrogen-potassium ATPase enzyme system (proton pump) in the gastric parietal cells. This reduces the final step of gastric acid production, leading to decreased acid secretion in the stomach. Its dual delayed-release technology allows two separate releases of the drug, resulting in extended acid suppression over a 24-hour period.

Indications

Dexoprex Capsule 60 mg is indicated for:

• Gastroesophageal reflux disease (GERD)
• Healing of erosive esophagitis
• Maintenance therapy after healing of esophageal damage
• Relief of heartburn and acid regurgitation
• Treatment of hypersecretory conditions (as prescribed)

Dosage and Administration

• To be taken orally once daily as directed by a physician
• Can be taken with or without food
• Capsule should be swallowed whole; do not crush or chew
• Treatment duration depends on condition severity and clinical response
• Regular evaluation is recommended for long-term use

Contraindications

Dexoprex Capsule should not be used in:

• Known hypersensitivity to Dexlansoprazole or other proton pump inhibitors
• Severe allergic reactions to substituted benzimidazoles
• Patients requiring immediate relief of acute gastric symptoms without medical supervision

Side Effects

Possible side effects include:

• Headache
• Diarrhea or constipation
• Nausea
• Abdominal pain
• Flatulence
• Dizziness
• Long-term use may lead to vitamin B12 deficiency or bone fracture risk

Precautions

• Use cautiously in patients with liver impairment
• Long-term therapy should be monitored for magnesium and vitamin B12 levels
• May increase risk of gastrointestinal infections (e.g., C. difficile)
• Not intended for immediate relief of acute heartburn symptoms
• Use lowest effective dose for the shortest duration possible

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Drug Interactions

Dexoprex Capsule may interact with:

• Drugs requiring gastric pH for absorption (e.g., ketoconazole, iron salts)
• Clopidogrel (may reduce activation in some cases)
• Methotrexate (increased levels with high-dose therapy)
• Warfarin (requires monitoring of INR)

Storage Conditions

• Store below 30°C in a dry place
• Protect from moisture and direct sunlight
• Keep out of reach of children.