Anaflex Max Tablet 375 mg+20 mg combines Naproxen Sodium 375 mg, a non-steroidal anti-inflammatory drug (NSAID), with Esomeprazole Magnesium 20 mg, a proton pump inhibitor (PPI). This combination provides effective pain and inflammation relief while reducing the risk of stomach irritation, ulcers, and discomfort commonly associated with long-term NSAID use. It is particularly suitable for patients requiring moderate-dose anti-inflammatory therapy with gastrointestinal protection.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Active Ingredients:
  • Naproxen Sodium 375 mg (for pain and inflammation relief)
  • Esomeprazole Magnesium 20 mg (to protect the stomach lining by reducing gastric acid)

Mechanism of Action

• Naproxen Sodium works by inhibiting cyclooxygenase (COX) enzymes, reducing prostaglandin production, which alleviates pain, inflammation, and swelling in joints, muscles, and tissues.
• Esomeprazole Magnesium suppresses gastric acid secretion, protecting the stomach lining from irritation and potential NSAID-induced ulcers.

Indications

Anaflex Max Tablet 375 mg+20 mg is indicated for:

• Osteoarthritis, rheumatoid arthritis, and other chronic musculoskeletal conditions
• Ankylosing spondylitis
• Moderate to severe acute musculoskeletal pain or soft tissue injuries
• Patients at risk of gastrointestinal complications due to NSAID therapy
• Long-term NSAID therapy requiring gastric protection

Dosage and Administration

• Adults: One tablet once daily, or as directed by a physician.
• Swallow the tablet whole with water, preferably before meals.
• Do not crush or chew the tablet to maintain the protective effect of Esomeprazole.
• Complete the full course as prescribed to achieve optimal outcomes.

Benefits

• Provides targeted relief from pain, inflammation, and stiffness
• Reduces risk of NSAID-induced gastric irritation and ulcers
• Convenient single tablet formulation combining efficacy and gastrointestinal protection
• Suitable for both acute and chronic inflammatory conditions
• Supports adherence and improved quality of life for long-term therapy

Possible Side Effects

Common side effects may include:

• Nausea, heartburn, or mild abdominal discomfort
• Headache or dizziness
• Mild allergic reactions (rash or itching)

Serious but rare side effects may include:

• Gastrointestinal bleeding
• Liver or kidney function disturbances
• Severe hypersensitivity reactions

Precautions and Warnings

• Take exactly as prescribed; do not exceed the recommended dose.
• Use cautiously in patients with liver, kidney, or heart conditions.
• Avoid during the third trimester of pregnancy unless directed by a physician.
• Consult a doctor before use during breastfeeding.
• Avoid concurrent use of other NSAIDs or PPIs unless advised by a healthcare professional.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Drug Interactions

Anaflex Max Tablet may interact with:

• Anticoagulants (e.g., warfarin) – increased bleeding risk
• Corticosteroids or other NSAIDs – increased risk of gastrointestinal irritation
• Certain antifungals, antivirals, or antiretroviral drugs – may affect absorption of Esomeprazole
• Lithium, digoxin, or certain antiepileptic drugs

Storage Instructions

• Store below 30°C in a cool, dry place
• Protect from light and moisture
• Keep out of reach of children.