Dentro Capsule 50 mg contains Dantrolene Sodium, a medication that works directly on muscle fibers to reduce excessive muscle contraction. It is commonly used in conditions involving severe muscle spasticity and as an emergency treatment for a rare but life-threatening condition called malignant hyperthermia.

Unlike many other muscle relaxants, Dantrolene acts directly on skeletal muscles rather than the central nervous system.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

Each capsule contains:

• Dantrolene Sodium 50 mg

It is intended for oral administration.

Mechanism of Action

Dantrolene works by acting on muscle cells:

• Inhibits release of calcium from the sarcoplasmic reticulum
• Reduces muscle contraction strength
• Decreases excessive muscle rigidity and spasms
• Helps normalize muscle tone

This direct muscle action helps relieve spasticity without major central nervous system depression.

Indications

Dentro Capsule 50 mg is indicated for:

• Spasticity
• Cerebral Palsy
• Malignant Hyperthermia
• Muscle stiffness due to neurological disorders or spinal cord injury

Dosage and Administration

• Dosage is individualized based on condition and severity
• Usually taken 1–3 times daily
• Should be taken with or without food
• Dose may be gradually increased under medical supervision

In malignant hyperthermia, it is used in hospital emergency settings.

Benefits

Dentro Capsule provides several benefits:

• Reduces muscle stiffness and spasticity
• Improves mobility and functional ability
• Helps manage neurological muscle disorders
• Life-saving role in malignant hyperthermia
• Acts directly on muscle tissue for targeted relief

Possible Side Effects

Common side effects include:

• Drowsiness or dizziness
• Weakness
• Diarrhea
• Fatigue

Serious side effects may include:

• Liver toxicity (hepatotoxicity)
• Muscle weakness
• Respiratory difficulty (rare)
• Allergic reactions

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions

• Regular monitoring of liver function is required during long-term use
• Use cautiously in patients with liver disease
• Avoid driving if drowsiness occurs
• Not recommended without medical supervision for long-term use
• Use carefully in elderly patients

Storage

Store in a cool, dry place below 30°C, protected from light and moisture. Keep out of reach of children.