Demoxiclave Tablet 250 mg+125 mg is a combination antibiotic containing Amoxicillin 250 mg and Clavulanic Acid 125 mg. This formulation is designed to effectively treat a wide variety of bacterial infections by enhancing the antibacterial action of amoxicillin and overcoming resistance caused by beta-lactamase–producing organisms.

Amoxicillin is a broad-spectrum penicillin antibiotic that works by inhibiting the synthesis of bacterial cell walls, ultimately leading to bacterial death. However, some bacteria produce enzymes called beta-lactamases that can destroy amoxicillin before it acts. Clavulanic acid is a beta-lactamase inhibitor that protects amoxicillin from breakdown, thereby expanding its antibacterial coverage. The combination ensures improved effectiveness against resistant strains of bacteria.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Demoxiclave Tablet 250 mg+125 mg is commonly prescribed for mild to moderate infections such as:

• Upper respiratory tract infections including sinusitis, pharyngitis, and tonsillitis

• Lower respiratory tract infections such as bronchitis and pneumonia

• Ear infections (otitis media)

• Urinary tract infections

• Skin and soft tissue infections

• Dental infections

Its broad-spectrum activity makes it suitable for infections caused by both Gram-positive and Gram-negative organisms.

Dosage and Administration

The dosage should be determined by a qualified healthcare professional based on the patient’s age, weight, severity of infection, and kidney function.

• Usually taken every 8 hours or as directed by the physician

• Should be taken at the beginning of a meal to minimize gastrointestinal discomfort

• Complete the entire prescribed course even if symptoms improve earlier

Do not miss doses or stop the medication prematurely, as this may lead to treatment failure or antibiotic resistance.

Precautions

• Contraindicated in patients with known hypersensitivity to penicillin or beta-lactam antibiotics

• Use cautiously in patients with liver or renal impairment

• Patients with a history of antibiotic-associated colitis should consult a doctor before use

• Prolonged use may increase the risk of secondary infections

Possible Side Effects

Common side effects may include:

• Nausea

• Vomiting

• Diarrhea

• Abdominal pain

• Skin rash

In rare cases, serious allergic reactions may occur. Immediate medical attention is required if symptoms such as difficulty breathing, severe rash, or facial swelling appear.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Drug Interactions

Demoxiclave may interact with:

• Oral contraceptives

• Anticoagulants (e.g., warfarin)

• Allopurinol

• Probenecid

Patients should inform their healthcare provider about all ongoing medications to avoid potential interactions.

Storage

• Store below 30°C

• Keep in a cool, dry place

• Protect from light and moisture

• Keep out of reach of children

Demoxiclave Tablet 250 mg+125 mg provides dependable antibacterial coverage for various infections when used under proper medical supervision.