Dactus Tablet 3 mg contains Glimepiride, a sulfonylurea class oral antidiabetic medication, designed to manage type 2 diabetes mellitus. It is used to lower elevated blood sugar levels in adults and adolescents over 18 years when diet, exercise, and lifestyle modifications alone are insufficient. Glimepiride works by stimulating insulin release from the pancreatic beta cells and improving insulin sensitivity in peripheral tissues. Dactus Tablet 3 mg is an effective choice for maintaining glycemic control and reducing the risk of long-term complications, including cardiovascular disease, kidney dysfunction, and neuropathy.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Active Ingredient: Glimepiride 3 mg

• Dosage Form: Oral tablet

• Route of Administration: Oral

Mechanism of Action

Glimepiride lowers blood glucose through a dual mechanism:

1. Stimulation of insulin secretion: By binding to sulfonylurea receptors on pancreatic beta cells, Glimepiride closes ATP-sensitive potassium channels, leading to cell depolarization, calcium influx, and increased insulin release.

2. Enhancement of insulin sensitivity: Glimepiride increases the efficiency of insulin in peripheral tissues, such as skeletal muscles, and reduces glucose production by the liver.

This dual action allows Dactus Tablet to reduce both fasting and postprandial blood glucose levels effectively, promoting overall metabolic stability in diabetic patients.

Indications

Dactus Tablet 3 mg is indicated for:

• Management of type 2 diabetes mellitus in adults and adolescents above 18 years

• Patients with insufficient glycemic control on diet and lifestyle measures alone

• Use as monotherapy or in combination with other oral hypoglycemic agents or insulin therapy

• Prevention of long-term complications associated with chronic hyperglycemia, such as cardiovascular disease, retinopathy, nephropathy, and neuropathy

Dosage and Administration

• Typical starting dose: 1–3 mg once daily, taken with breakfast or the first main meal to minimize hypoglycemia risk

• Dose may be adjusted according to blood glucose monitoring, up to a maximum of 8 mg per day

• Swallow the tablet with water; do not crush or chew

• Consistent adherence to diet, exercise, and blood glucose monitoring is essential for optimal results

• Avoid skipping meals to reduce the risk of hypoglycemia

Contraindications

Dactus Tablet 3 mg should not be used in:

• Patients with hypersensitivity to Glimepiride or other sulfonylureas

• Type 1 diabetes mellitus

• Diabetic ketoacidosis

• Severe renal or hepatic impairment

• Pregnant or breastfeeding women unless directed by a healthcare professional

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions and Warnings

• Risk of hypoglycemia, especially in elderly patients, irregular eaters, or those taking other antidiabetic medications

• Use with caution in patients with kidney or liver dysfunction

• Dose adjustments may be necessary in elderly patients

• Inform your physician of all concurrent medications to prevent drug interactions

Possible Side Effects

Dactus Tablet 3 mg is generally well tolerated. Common side effects may include:

• Hypoglycemia (low blood sugar)

• Nausea, vomiting, or gastrointestinal discomfort

• Dizziness or headache

• Rare effects: allergic reactions, skin rashes, liver enzyme alterations, or hematologic abnormalities

Storage

Store in a cool, dry place below 30°C. Protect from moisture and light. Keep out of reach of children.

Conclusion

Dactus Tablet 3 mg is a reliable option for managing type 2 diabetes mellitus. By stimulating insulin secretion and enhancing insulin sensitivity, it helps maintain stable blood glucose levels and reduce the risk of diabetes-related complications. When combined with diet, exercise, and regular monitoring, Dactus Tablet 3 mg provides safe and effective glycemic control under medical supervision.