Dabiren Capsule 75 mg contains Dabigatran Etexilate Mesylate, an oral anticoagulant used to prevent and treat blood clots. Dabigatran is a direct thrombin inhibitor that works by blocking thrombin, a key enzyme in the coagulation process, thereby reducing the formation of fibrin and preventing clot formation.

Dabiren Capsule is commonly prescribed for patients with atrial fibrillation (irregular heart rhythm) to reduce the risk of stroke and systemic embolism, and for the prevention or treatment of deep vein thrombosis (DVT) and pulmonary embolism (PE). Unlike traditional anticoagulants, it does not require routine blood monitoring for dose adjustment in most patients.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন.

Composition

Each capsule contains:

• Dabigatran Etexilate Mesylate 75 mg

Mechanism of Action

Dabigatran is a prodrug that is converted in the body to active dabigatran. Active dabigatran directly inhibits thrombin (factor IIa), preventing the conversion of fibrinogen to fibrin. By targeting thrombin directly, it prevents clot formation while reducing the risk of excessive bleeding associated with some other anticoagulants.

Indications

Dabiren Capsule 75 mg is indicated for:

• Prevention of stroke and systemic embolism in patients with non-valvular atrial fibrillation

• Treatment and prevention of recurrence of deep vein thrombosis (DVT)

• Treatment and prevention of pulmonary embolism (PE)

• Postoperative prevention of venous thromboembolism in patients undergoing hip or knee replacement surgery

Dosage and Administration

• The standard dose is 75 mg taken orally twice daily, or as prescribed by a healthcare professional.

• Swallow the capsule whole with water; do not crush or chew.

• Can be taken with or without food.

• Take the capsule at the same times each day for consistent anticoagulant effect.

• Follow your doctor’s instructions regarding dose adjustments in kidney impairment.

Precautions

• Use cautiously in patients with kidney or liver disease.

• Inform your doctor of any history of bleeding disorders or gastrointestinal ulcers.

• Avoid use in patients with mechanical heart valves.

• Pregnancy and breastfeeding: only use if prescribed by a healthcare professional.

• Avoid abrupt discontinuation to reduce the risk of thromboembolic events.

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন.

Possible Side Effects

Common side effects may include:

• Bleeding from gums, nose, or minor cuts

• Bruising or prolonged bleeding

• Gastrointestinal discomfort or nausea

• Rare allergic reactions

Serious bleeding events require immediate medical attention.

Storage

• Store below 25°C in a cool, dry place

• Keep the container tightly closed and protected from moisture

• Keep out of reach of children

Dabiren Capsule 75 mg is a reliable anticoagulant for preventing and managing blood clots. When used under medical supervision, it helps reduce the risk of stroke, DVT, and pulmonary embolism safely and effectively.