Cortiment Tablet 9 mg is a potent anti-inflammatory medication containing Budesonide, a corticosteroid specifically formulated for the management of inflammatory bowel diseases (IBD), such as ulcerative colitis and other mild to moderate inflammatory conditions of the colon. Cortiment is designed to deliver targeted action to the colon, reducing inflammation while minimizing systemic steroid exposure.

Budesonide is a glucocorticoid that works by suppressing the inflammatory response in the intestinal mucosa. It inhibits the release of pro-inflammatory cytokines, chemokines, and other mediators, reducing swelling, redness, and tissue damage. Its high first-pass metabolism in the liver allows for effective local activity in the gut while limiting systemic corticosteroid side effects.

Cortiment 9 mg is particularly useful for inducing and maintaining remission in patients with mild to moderate ulcerative colitis and other colonic inflammatory conditions. Its targeted release formulation ensures that the drug is released in the lower gastrointestinal tract, providing focused relief and reducing systemic exposure.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Therapeutic Class

• Corticosteroid

• Anti-inflammatory Agent

• Gastrointestinal Therapy

Composition

Each tablet contains:

• Budesonide: 9 mg

The formulation ensures delayed release, allowing the drug to act directly in the colon for optimal therapeutic effect.

Indications

Cortiment Tablet 9 mg is indicated for:

• Induction of remission in mild to moderate ulcerative colitis

• Management of other localized inflammatory conditions of the colon

• Maintenance therapy in patients requiring reduced systemic corticosteroid exposure

• Patients intolerant to conventional systemic corticosteroids or needing long-term therapy

Mechanism of Action

Budesonide, the active ingredient in Cortiment, exerts its effect through the following mechanisms:

• Binds to glucocorticoid receptors in the intestinal mucosa

• Suppresses pro-inflammatory cytokine production

• Reduces leukocyte migration and edema

• Inhibits inflammatory enzyme activity in the colon

• Promotes mucosal healing and tissue repair

The targeted release formulation ensures that Budesonide reaches the distal ileum and colon, providing localized anti-inflammatory action with minimal systemic absorption.

Dosage and Administration

• Recommended dose: 9 mg once daily

• Tablets should be swallowed whole with water, preferably in the morning

• Can be taken with or without food

• Treatment duration and dosage may be adjusted by the physician based on disease severity and patient response

• Regular monitoring of disease activity is advised during therapy

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Possible Side Effects

Cortiment Tablet 9 mg is generally well tolerated due to its localized action. Potential side effects may include:

• Headache

• Mild gastrointestinal discomfort

• Nausea

• Rare systemic corticosteroid effects such as weight gain, increased blood sugar, or adrenal suppression

Long-term use should be monitored by a healthcare professional.

Precautions and Warnings

• Use caution in patients with active infections or systemic fungal infections

• Avoid abrupt discontinuation of therapy; tapering may be required in long-term use

• Not recommended for pregnancy or lactation unless prescribed by a physician

• Monitor patients for glucose levels, bone health, and adrenal function during prolonged therapy

• Patients with liver impairment should use under careful supervision

Storage

• Store in a cool, dry place below 30°C

• Protect from light and moisture

• Keep out of reach of children.