Corofree Tablet 200 mg contains Hydroxychloroquine Sulphate, an antimalarial and immunomodulatory medicine used for the treatment and prevention of malaria caused by susceptible Plasmodium species and for the long-term management of rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE). It helps control inflammation, reduce disease activity, and prevent disease flare-ups, improving the quality of life for patients with autoimmune disorders.

Hydroxychloroquine has multiple mechanisms of action depending on the condition being treated. In autoimmune diseases such as rheumatoid arthritis and lupus, it modulates the immune system by interfering with antigen presentation, reducing inflammatory cytokine production, and decreasing abnormal immune cell activity. This helps relieve joint pain, swelling, stiffness, skin manifestations, and fatigue while slowing disease progression.

As an antimalarial agent, Hydroxychloroquine accumulates within the malaria parasite and interferes with its ability to detoxify heme, leading to parasite death. However, due to widespread resistance in some regions, its use for malaria should follow current local treatment guidelines.

Corofree Tablet 200 mg is generally intended for long-term therapy in autoimmune diseases. Clinical improvement in rheumatoid arthritis or lupus may take several weeks to months of continuous treatment. Because prolonged use may rarely affect the retina, regular ophthalmic examinations are recommended, particularly in patients receiving long-term treatment or higher cumulative doses.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Corofree Tablet 200 mg is indicated for:

• Rheumatoid arthritis (RA)
• Systemic lupus erythematosus (SLE)
• Discoid lupus erythematosus
• Treatment of susceptible malaria
• Prevention of susceptible malaria (where appropriate according to local guidelines)

How Corofree Tablet Works

Hydroxychloroquine modifies immune system activity by reducing inflammatory responses and abnormal immune cell activation, helping control autoimmune diseases such as rheumatoid arthritis and lupus. In malaria, it interferes with the parasite's ability to metabolize heme, resulting in parasite death.

Benefits of Corofree Tablet

• Helps relieve joint pain, swelling, and stiffness in rheumatoid arthritis.
• Reduces lupus flare-ups and improves disease control.
• Helps manage skin and joint symptoms associated with lupus.
• Effective for the treatment and prevention of susceptible malaria.
• Supports long-term management of autoimmune diseases.
• May reduce the need for higher doses of corticosteroids in some patients.
• Well-established safety and efficacy when used under medical supervision.

Dosage and Administration

Take Corofree Tablet 200 mg exactly as prescribed by your healthcare provider.

• Swallow the tablet whole with a glass of water.
• Take the medicine with food or milk to help reduce stomach upset.
• Take it at the same time each day.
• Continue treatment regularly, even if you do not notice immediate improvement.
• Do not stop taking the medication without consulting your healthcare provider.

Regular eye examinations and periodic monitoring of blood counts and liver function may be recommended during long-term therapy.

Possible Side Effects

Like all medicines, Corofree Tablet may cause side effects, although not everyone experiences them.

Common side effects include:

• Nausea
• Vomiting
• Diarrhea
• Abdominal discomfort
• Headache
• Dizziness
• Skin rash

Less common but serious side effects may include:

• Retinal toxicity and vision changes
• Severe allergic reactions
• Heart rhythm disturbances (QT prolongation)
• Muscle weakness
• Low blood sugar (hypoglycemia)
• Blood disorders

Seek immediate medical attention if you experience blurred vision, changes in color vision, severe skin reactions, chest pain, irregular heartbeat, severe weakness, or symptoms of an allergic reaction.

Precautions and Warnings

Before taking Corofree Tablet, inform your healthcare provider if you have:

• Eye disease or vision problems
• Heart disease or abnormal heart rhythm
• Liver or kidney disease
• Psoriasis
• Glucose-6-phosphate dehydrogenase (G6PD) deficiency
• Diabetes
• Pregnancy or breastfeeding

Inform your healthcare provider about all prescription medicines, over-the-counter drugs, vitamins, and herbal supplements you are taking, as Hydroxychloroquine may interact with several medications, including drugs that affect heart rhythm.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Storage

Store below 30°C in a cool, dry place, protected from moisture and direct sunlight. Keep the tablets in their original packaging and out of the reach of children.

Disclaimer

Corofree Tablet 200 mg is a prescription medicine and should only be used under the supervision of a qualified healthcare professional. Regular medical follow-up and eye examinations are recommended during long-term treatment to monitor for potential side effects. Always follow your healthcare provider's instructions regarding dosage and duration of therapy.