Cefobac Injection 750 mg/vial contains Cefuroxime Axetil, a second-generation cephalosporin antibiotic used to treat a wide range of bacterial infections. It is effective against both Gram-positive and Gram-negative bacteria and is commonly used for respiratory tract infections, urinary tract infections, skin and soft tissue infections, and other bacterial infections requiring parenteral therapy.

Cefuroxime works by inhibiting bacterial cell wall synthesis, leading to bacterial lysis and death. The injectable formulation ensures rapid therapeutic action and is particularly useful in hospitalized patients or cases where oral antibiotics are not suitable.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Key Benefits

• Broad-spectrum antibacterial activity
• Effective against respiratory, urinary, and skin infections
• Injectable form ensures fast onset of action
• Suitable for hospitalized patients or severe infections
• Well-tolerated with a favorable safety profile

Indications

Cefobac Injection 750 mg/vial is indicated for:

• Lower respiratory tract infections, including pneumonia and bronchitis
• Urinary tract infections
• Skin and soft tissue infections
• Bone and joint infections
• Septicemia and other systemic bacterial infections
• Pre- and post-operative prophylaxis in susceptible patients

Mechanism of Action

Cefuroxime is a β-lactam antibiotic that:

• Inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs)
• Disrupts bacterial cell wall integrity, causing cell lysis
• Exhibits bactericidal action against susceptible pathogens

Dosage and Administration

• Administered by a healthcare professional via intravenous (IV) or intramuscular (IM) injection
• Typical adult dose: 750 mg every 8–12 hours, depending on infection severity
• Pediatric dosing is weight-based and determined by a physician
• Dose adjustment required in patients with renal impairment
• Reconstitute and administer as per instructions to minimize local irritation

Side Effects

Common side effects:

• Injection site pain, redness, or swelling
• Nausea, vomiting, or diarrhea
• Mild headache

Rare side effects:

• Allergic reactions such as rash, itching, or anaphylaxis
• Liver or kidney function alterations
• Blood disorders including neutropenia or thrombocytopenia

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions and Warnings

• Use with caution in patients with a history of penicillin or cephalosporin allergy
• Monitor renal function during prolonged therapy
• Observe for superinfections with long-term use
• Adjust dosage in patients with renal impairment

Contraindications

• Hypersensitivity to Cefuroxime, other cephalosporins, or β-lactam antibiotics
• History of severe allergic reactions to penicillin

Storage Instructions

• Store below 30°C in a dry, dark place
• Protect from light
• Keep out of reach of children.