Cardizem SR Tablet 120 mg contains Diltiazem Hydrochloride, a sustained-release calcium channel blocker used in the management of cardiovascular disorders such as hypertension, angina pectoris, and certain arrhythmias. Unlike immediate-release formulations, the sustained-release (SR) formulation allows gradual release of the active ingredient, providing a prolonged therapeutic effect over 24 hours. This reduces the frequency of dosing, improves patient compliance, and ensures stable blood pressure and heart rate control throughout the day.

Diltiazem works by inhibiting the influx of calcium ions into cardiac and vascular smooth muscle cells, leading to relaxation of blood vessels, reduced cardiac workload, and improved coronary blood flow. It also slows conduction through the atrioventricular (AV) node, helping to control certain supraventricular arrhythmias and prevent rapid heart rates.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Cardizem SR Tablet 120 mg is indicated for:

• Hypertension (high blood pressure) to prevent cardiovascular complications such as stroke, heart attack, and kidney damage

• Chronic stable angina to relieve chest pain and improve exercise tolerance

• Variant (Prinzmetal’s) angina caused by coronary artery spasms

• Supraventricular arrhythmias, including atrial fibrillation and atrial flutter, for heart rate control

• Long-term management to prevent recurrent angina attacks and improve overall cardiac function

The sustained-release formulation makes it especially suitable for patients who require once-daily dosing for convenience and consistent therapeutic effect.

Key Benefits

• Provides once-daily blood pressure and heart rate control

• Reduces chest pain and frequency of angina attacks

• Controls heart rate in atrial fibrillation or supraventricular tachycardia

• Improves oxygen supply to the heart and overall cardiac function

• Enhances patient compliance due to sustained-release formulation

• Can be used alone or in combination with other cardiovascular medications

Dosage and Administration

The dosage of Cardizem SR Tablet 120 mg should be individualized based on the patient’s condition, response, and coexisting health factors.

General administration guidelines:

• Adults: typically 120 mg once daily, with or without food, or as prescribed by a physician

• Swallow the tablet whole; do not crush, chew, or split the SR tablet

• Take at the same time every day to maintain consistent blood pressure and heart rate

• Regular monitoring of blood pressure, heart rate, and ECG is recommended

Dose adjustments may be necessary for patients with liver impairment, heart block, or other cardiovascular conditions.

Precautions

Before using Cardizem SR Tablet, consult your doctor if you have:

• Severe bradycardia (slow heart rate) or AV block

• Heart failure or recent myocardial infarction

• Low blood pressure or hypotension

• Liver or kidney disease

• Pregnancy or breastfeeding

Caution is advised when used with other antihypertensive, antiarrhythmic, or beta-blocker medications. Abrupt discontinuation should be avoided, as it may worsen angina or precipitate arrhythmias.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Possible Side Effects

Cardizem SR Tablet 120 mg is generally well tolerated. Common side effects may include:

• Dizziness or lightheadedness

• Headache or fatigue

• Swelling of ankles or feet (peripheral edema)

• Gastrointestinal discomfort such as nausea or constipation

• Mild palpitations

Rare but serious side effects may include:

• Severe hypotension

• Heart block or arrhythmias

• Liver enzyme abnormalities

• Allergic reactions

Seek immediate medical attention if severe symptoms such as fainting, shortness of breath, or severe chest pain occur.

Storage

Store below 30°C in a cool, dry place, protected from light and moisture. Keep out of reach of children.

Cardizem SR Tablet 120 mg provides effective, long-lasting management of hypertension, angina, and certain arrhythmias, supporting heart health and improving quality of life under proper medical supervision.