Candistin Ear Drop is a multicomponent otic preparation formulated for the treatment of infected and inflamed ear conditions. It contains Ofloxacin 0.3%, Clotrimazole 1%, Beclomethasone 0.025%, and Lidocaine 2%, offering a comprehensive therapeutic approach by combining antibacterial, antifungal, anti-inflammatory, and analgesic properties.

This combination is particularly effective in managing acute and chronic otitis externa, fungal ear infections, and inflammatory ear conditions, providing rapid relief from pain, itching, inflammation, and discharge. The formulation is designed for topical application, allowing direct action at the site of infection while minimizing systemic absorption.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Ofloxacin 0.3% – a broad-spectrum antibiotic effective against Gram-positive and Gram-negative bacteria

• Clotrimazole 1% – an antifungal agent for treatment of otomycosis and fungal infections

• Beclomethasone 0.025% – a corticosteroid that reduces inflammation, swelling, and irritation

• Lidocaine 2% – a local anesthetic providing rapid pain relief

Mechanism of Action

Candistin Ear Drop works through the synergistic action of its components:

1. Ofloxacin (Antibacterial)

   • Inhibits bacterial DNA gyrase and topoisomerase IV

   • Prevents bacterial replication and eliminates infection

2. Clotrimazole (Antifungal)

   • Disrupts fungal cell membrane integrity by inhibiting ergosterol synthesis

   • Effective against Candida and Aspergillus species causing otomycosis

3. Beclomethasone (Anti-inflammatory)

   • Reduces inflammation, redness, and edema of the external auditory canal

   • Helps relieve swelling, itching, and irritation

4. Lidocaine (Analgesic)

   • Provides rapid local pain relief by blocking nerve conduction in the affected area

By addressing infection, inflammation, and pain simultaneously, Candistin ensures quick symptom relief and promotes faster recovery.

Indications

Candistin Ear Drop is indicated for:

• Acute otitis externa caused by bacterial or fungal infections

• Chronic otitis externa with persistent inflammation

• Otomycosis (fungal infection of the external ear)

• Painful or itchy ear conditions associated with infection or inflammation

• Post-ear procedures to reduce inflammation and discomfort

Benefits

• Broad-Spectrum Antimicrobial Action: Combines antibacterial and antifungal activity

• Rapid Symptom Relief: Lidocaine provides immediate pain control

• Reduces Inflammation: Beclomethasone alleviates swelling, redness, and irritation

• Convenient Topical Application: Direct delivery to affected ear ensures maximum efficacy

• Supports Faster Healing: Addresses multiple aspects of ear infections in a single formulation

• Safe and Well-Tolerated: Minimal systemic absorption reduces the risk of systemic side effects

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Dosage and Administration

• Adults and children (over 1 year): 2–3 drops into the affected ear 2–3 times daily, or as prescribed

• Gently shake the bottle before use

• Tilt the head to allow the drops to reach the ear canal; keep the head tilted for 2–3 minutes

• Avoid contamination of the dropper tip with the ear or hands

• Continue treatment for the entire prescribed duration, even if symptoms improve

Safety and Precautions

• Common side effects: mild burning, itching, or temporary ear discomfort

• Rare side effects: allergic reactions, local irritation, or transient dizziness

• Contraindicated in patients with hypersensitivity to any of the components

• Avoid contact with eyes; rinse immediately if accidental contact occurs

• Do not use in perforated eardrum without medical supervision

• Pregnant and breastfeeding women should use only under medical advice.