Avloclav Tablet 875 mg+125 mg is a broad-spectrum antibiotic that combines Amoxicillin 875 mg with Clavulanic Acid 125 mg. This combination is effective against a wide range of bacterial infections, including those caused by beta-lactamase-producing bacteria, which are resistant to amoxicillin alone. Amoxicillin works by inhibiting bacterial cell wall synthesis, while Clavulanic Acid prevents the degradation of amoxicillin by bacterial enzymes, ensuring maximum antibacterial activity.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Amoxicillin: 875 mg – a penicillin-class antibiotic that disrupts bacterial cell wall formation
• Clavulanic Acid: 125 mg – a beta-lactamase inhibitor that protects amoxicillin from enzymatic breakdown

Mechanism of Action

• Amoxicillin: Binds to bacterial penicillin-binding proteins (PBPs), inhibiting cell wall synthesis, which leads to bacterial death
• Clavulanic Acid: Inhibits beta-lactamase enzymes, allowing amoxicillin to remain effective against resistant bacteria
• Provides enhanced antibacterial efficacy against Gram-positive and Gram-negative pathogens

Indications

Avloclav Tablet 875 mg+125 mg is used to treat:

• Respiratory tract infections: pneumonia, bronchitis, sinusitis
• Ear, nose, and throat infections: tonsillitis, pharyngitis, otitis media
• Urinary tract infections
• Skin and soft tissue infections: cellulitis, abscesses, wound infections
• Dental infections
• Bone and joint infections and other infections caused by susceptible bacteria

Dosage and Administration

• Adults and children over 12 years: 1 tablet every 12 hours, or as directed by a physician
• Swallow the tablet whole with a glass of water; it can be taken with or without food
• Complete the full prescribed course, even if symptoms improve early
• Do not split, crush, or chew the tablet

Benefits

• Effective against resistant bacterial strains
• Treats a wide range of respiratory, urinary, skin, dental, and soft tissue infections
• Prevents treatment failure due to beta-lactamase-producing bacteria
• Convenient high-strength tablet for adults and older children
• Supports rapid recovery from moderate to severe bacterial infections

Possible Side Effects

Common side effects:

• Nausea, vomiting, diarrhea
• Mild rash or itching
• Headache

Rare but serious side effects:

• Severe allergic reactions (anaphylaxis, swelling, difficulty breathing)
• Liver enzyme elevation or jaundice
• Clostridium difficile-associated diarrhea

Precautions and Warnings

• Contraindicated in patients with penicillin allergy
• Use cautiously in patients with renal impairment
• Monitor for signs of allergic reactions or severe gastrointestinal symptoms
• Not effective against viral infections
• Inform your physician of all other medications being taken

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Drug Interactions

• May interact with oral anticoagulants, methotrexate, allopurinol, and other antibiotics
• May reduce effectiveness of oral contraceptives
• Dose adjustment may be needed in patients with renal dysfunction

Storage Instructions

• Store at 15–25°C in a cool, dry place, protected from light
• Keep the tablet in its original packaging until use
• Keep out of reach of children
• Do not use after the expiry date.