Arsenor Tablet 10 mg contains Apremilast, an oral phosphodiesterase-4 (PDE4) inhibitor used in the management of inflammatory autoimmune conditions. It works by regulating the immune system and reducing excessive inflammatory responses. This lower-strength tablet is mainly used during the initial dose titration phase to improve tolerability and minimize gastrointestinal side effects before reaching the maintenance dose.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Active Ingredient: Apremilast 10 mg per tablet

Mechanism of Action

Apremilast inhibits phosphodiesterase-4 (PDE4), an enzyme responsible for breaking down cyclic adenosine monophosphate (cAMP). By increasing intracellular cAMP levels, it helps suppress the production of pro-inflammatory cytokines such as TNF-alpha, IL-17, and IL-23. This leads to reduced inflammation in skin and joint tissues.

Indications

Arsenor Tablet is indicated for:

• Moderate to severe plaque psoriasis
• Active psoriatic arthritis
• Initial dose titration phase of Apremilast therapy
• Other inflammatory autoimmune conditions as prescribed by a physician

Dosage and Administration

• Used primarily as part of a step-up titration schedule
• Taken orally with or without food
• Tablets should be swallowed whole with water
• The dosing schedule is gradually increased to reduce gastrointestinal side effects before reaching the maintenance dose
• Follow physician instructions strictly for titration

Benefits

• Helps improve tolerability during treatment initiation
• Reduces inflammation in psoriasis and psoriatic arthritis
• Oral administration provides convenient therapy
• Supports gradual adaptation to full therapeutic dose
• Contributes to long-term disease control when used as directed

Possible Side Effects

Common side effects may include:

• Diarrhea
• Nausea
• Headache
• Abdominal discomfort
• Reduced appetite

Less common but serious side effects:

• Depression or mood changes
• Significant weight loss
• Hypersensitivity reactions

Patients should report persistent or severe symptoms to a healthcare provider.

Precautions and Warnings

• Use cautiously in patients with a history of depression or psychiatric illness
• Monitor body weight during treatment
• Dose adjustment may be required in severe renal impairment
• Not recommended during pregnancy unless clearly necessary
• Should be used under strict medical supervision

Drug Interactions

• Strong enzyme inducers (e.g., rifampicin, carbamazepine, phenytoin) may reduce effectiveness
• Inform healthcare provider about all medications being used
• Minimal interaction with most standard anti-inflammatory drugs

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Storage

• Store below 30°C
• Keep away from moisture and direct light
• Keep out of reach of children

Conclusion

Arsenor Tablet 10 mg (Apremilast) is an important starter dose in Apremilast therapy, designed to improve treatment tolerability while managing inflammatory conditions such as psoriasis and psoriatic arthritis. It plays a key role in achieving effective long-term disease control when used as part of a guided dose escalation plan.