Anaxyl Injection 500 mg/5 ml contains Tranexamic Acid, an antifibrinolytic agent used to prevent or reduce excessive bleeding. Tranexamic acid works by inhibiting the breakdown of blood clots, making it an essential medication in the management of surgical bleeding, heavy menstrual bleeding, trauma, and other conditions associated with abnormal blood loss. The injectable form allows rapid and controlled administration in hospital settings, ensuring effective and timely management of bleeding.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Active Ingredient: Tranexamic Acid 500 mg per 5 ml solution

Mechanism of Action

Tranexamic acid competitively inhibits the activation of plasminogen to plasmin, a key enzyme responsible for fibrinolysis (breakdown of blood clots). By preventing the dissolution of fibrin clots, Anaxyl Injection stabilizes formed clots and helps reduce ongoing bleeding.

Indications

Anaxyl Injection is indicated for:

• Prevention and treatment of excessive bleeding in surgeries, including dental, orthopedic, gynecological, and cardiac procedures
• Heavy menstrual bleeding (menorrhagia) when oral therapy is not feasible
• Trauma patients at risk of significant hemorrhage
• Bleeding disorders such as hemophilia, in combination with factor replacement therapy
• Control of bleeding in patients with liver disease or other coagulopathies

Dosage and Administration

• Administered intravenously by a healthcare professional.
• Typical adult dose: 10–15 mg/kg every 8 hours, or as prescribed by a physician.
• Can also be administered slowly via intravenous infusion or directly as a bolus injection, depending on clinical requirements.
• Dosage may need adjustment in patients with kidney impairment.
• Close monitoring of bleeding, coagulation parameters, and renal function is recommended during therapy.

Benefits

• Rapid and effective control of bleeding
• Useful in surgical, traumatic, and gynecological bleeding
• Helps reduce transfusion requirements
• Can be combined with other therapies for optimal hemostatic effect
• Injectable form allows precise dosing and immediate action

Possible Side Effects

Common side effects:

• Nausea or vomiting
• Diarrhea
• Mild headache or dizziness
• Local pain or irritation at injection site

Serious but rare side effects:

• Thromboembolic events (blood clots in veins or arteries)
• Allergic reactions, including rash, itching, or swelling
• Visual disturbances

Precautions and Warnings

• Use with caution in patients with a history of thromboembolic disease, such as deep vein thrombosis, pulmonary embolism, or stroke.
• Adjust dose in patients with renal impairment.
• Avoid rapid IV injection; administer slowly to prevent hypotension.
• Not recommended during pregnancy unless clearly necessary.
• Monitor coagulation parameters during prolonged therapy.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Drug Interactions

• May interact with oral contraceptives or hormone replacement therapy (increased clotting risk)
• Caution when used with anticoagulants or thrombolytic agents

Storage Instructions

• Store below 30°C in a cool, dry place
• Protect from light
• Keep out of reach of children
• Use immediately after opening the vial; discard any unused portion.