Amotrex DS Tablet 800 mg contains Metronidazole, a high-potency antimicrobial and antiprotozoal agent used to treat serious infections caused by anaerobic bacteria and certain protozoa. The “DS” (Double Strength) formulation allows for convenient once- or twice-daily dosing, ensuring effective therapy for gastrointestinal, gynecological, dental, and soft tissue infections while improving patient compliance.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Active Ingredient: Metronidazole 800 mg

Mechanism of Action

Metronidazole works by penetrating bacterial and protozoal cells and disrupting DNA synthesis, preventing replication and leading to cell death. It is particularly effective against anaerobic bacteria that thrive in low-oxygen environments, including the gastrointestinal tract, oral cavity, skin, and deep tissues.

Indications

Amotrex DS Tablet 800 mg is indicated for:

• Gastrointestinal infections, including amoebiasis and giardiasis
• Bacterial vaginosis and other gynecological infections
• Dental infections such as periodontitis and abscesses
• Skin and soft tissue infections caused by susceptible organisms
• Part of combination therapy for Helicobacter pylori eradication
• Treatment of anaerobic infections requiring higher doses for efficacy

Dosage and Administration

• Adults: Usually 800 mg once or twice daily, depending on infection type and severity.
• Take the tablet orally with a full glass of water, preferably after meals to reduce gastrointestinal discomfort.
• Complete the full prescribed course, even if symptoms improve, to prevent recurrence or resistance.
• Dosage adjustments may be required for patients with liver impairment.

Benefits

• High-potency “Double Strength” tablet for effective treatment
• Rapid relief from infection-related symptoms such as pain, inflammation, and diarrhea
• Targets anaerobic bacteria and protozoa efficiently
• Reduces frequency of dosing, improving adherence
• Convenient oral formulation for adults

Possible Side Effects

Common side effects may include:

• Nausea or vomiting
• Metallic taste in the mouth
• Abdominal discomfort or diarrhea
• Headache
• Dizziness

Rare but serious side effects may include neurological symptoms (peripheral neuropathy, seizures), severe allergic reactions, or blood abnormalities. Seek medical attention if serious symptoms occur.

Precautions and Warnings

• Avoid alcohol during treatment and for at least 48 hours afterward to prevent a disulfiram-like reaction.
• Use cautiously in patients with liver disease, kidney impairment, or neurological disorders.
• Not recommended during the first trimester of pregnancy unless prescribed by a physician.
• Consult a doctor before use during breastfeeding.
• Inform your healthcare provider about all medications being taken.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Drug Interactions

Amotrex DS Tablet may interact with:

• Warfarin (may increase bleeding risk)
• Lithium
• Certain antiepileptic drugs
• Alcohol (may trigger adverse reactions)

Storage Instructions

• Store below 30°C in a cool, dry place
• Protect from light and moisture
• Keep out of reach of children.