Adegra Tablet 50 mg contains Sildenafil Citrate, a phosphodiesterase type 5 (PDE5) inhibitor used for the treatment of erectile dysfunction (ED) in adult men. Sildenafil works by enhancing blood flow to the penis during sexual stimulation, enabling the achievement and maintenance of a firm erection.

Adegra is an effective and well-tolerated option for men with ED caused by vascular, neurological, or psychological factors. It provides rapid onset of action, typically within 30–60 minutes, and supports normal sexual function without causing spontaneous erections without stimulation.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Adegra Tablet 50 mg is indicated for:

• Treatment of erectile dysfunction (ED) in adult men
• Management of ED associated with conditions such as diabetes, hypertension, or post-surgical complications
• Support for sexual activity in men with psychological or performance-related ED

Mechanism of Action

Sildenafil Citrate works by:

• Inhibiting PDE5, an enzyme that breaks down cyclic guanosine monophosphate (cGMP) in the penile tissue
• Increasing levels of cGMP, leading to smooth muscle relaxation in the corpus cavernosum
• Enhancing blood flow to the penis during sexual stimulation, resulting in an erection
• Acting only in the presence of sexual stimulation; it does not cause an erection spontaneously

Dosage and Administration

• Recommended dose: 50 mg orally, as needed, approximately 30–60 minutes before sexual activity
• Swallow the tablet whole with water; can be taken with or without food (high-fat meals may delay onset)
• Maximum one dose per day
• Dose adjustment may be required in patients with renal or hepatic impairment, older adults, or those taking interacting medications
• Sexual stimulation is necessary for the medication to be effective

Side Effects

Common side effects:

• Headache
• Flushing (warmth or redness of the face)
• Indigestion or heartburn
• Nasal congestion
• Dizziness or mild visual disturbances (blue-tinged vision)

Rare but serious side effects:

• Priapism (erection lasting more than 4 hours – seek immediate medical attention)
• Severe hypotension or fainting
• Sudden vision or hearing loss

Discontinue use and consult a physician if serious side effects occur.

Precautions and Warnings

• Not for use in women or children
• Avoid use with nitrates or nitric oxide donors as it may cause severe hypotension
• Use caution in patients with cardiovascular disease, recent stroke, or myocardial infarction
• Alcohol consumption may reduce effectiveness

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Drug Interactions

Adegra Tablet may interact with:

• Nitrates – can cause dangerous low blood pressure
• Alpha-blockers – may lead to hypotension
• CYP3A4 inhibitors (e.g., ketoconazole, ritonavir) – may increase Sildenafil levels
• Other ED medications – should not be combined

Always inform your healthcare provider of all medications being taken.

Storage Instructions

• Store at 20–25°C (room temperature)
• Protect from moisture and light
• Keep in original packaging until use
• Keep out of reach of children
• Do not use after the expiry date.