Actose Tablet 15 mg contains Pioglitazone 15 mg, an oral antidiabetic medication indicated for the management of type 2 diabetes mellitus. It belongs to the thiazolidinedione class of medicines and works primarily by improving insulin sensitivity in the body. Actose is prescribed for patients whose blood glucose levels are not adequately controlled by lifestyle modification alone or who require additional therapy alongside other antidiabetic agents.

Type 2 diabetes is characterized by insulin resistance and impaired glucose metabolism. Actose helps address these underlying problems by enhancing the body’s response to insulin, leading to better glycemic control. It is intended to be used as part of a comprehensive diabetes management plan that includes proper diet, regular exercise, and routine blood sugar monitoring.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Pioglitazone 15 mg

Mechanism of Action

Pioglitazone works by activating peroxisome proliferator-activated receptor gamma (PPAR-γ) in adipose tissue, muscle, and liver cells. Activation of these receptors increases insulin sensitivity and promotes better glucose uptake by peripheral tissues.

As a result:

• Insulin resistance is reduced.

• Hepatic glucose production decreases.

• Peripheral glucose utilization improves.

• Blood glucose levels become more stable.

Unlike insulin secretagogues, Pioglitazone does not increase insulin secretion from the pancreas. Therefore, when used alone, the risk of hypoglycemia is relatively low.

Indications

Actose Tablet 15 mg is indicated for:

• Management of Type 2 Diabetes Mellitus

• Patients inadequately controlled by diet and exercise alone

• Monotherapy in suitable patients

• Combination therapy with other oral antidiabetic medicines such as metformin, sulfonylureas, or insulin when additional glycemic control is needed

Benefits

• Improves Insulin Sensitivity: Targets insulin resistance, a key factor in type 2 diabetes.

• Effective Glycemic Control: Helps reduce fasting blood glucose and HbA1c levels.

• Low Risk of Hypoglycemia: When used alone.

• Once-Daily Dosing: Enhances patient compliance.

• Supportive Metabolic Effects: May positively influence certain lipid parameters under medical supervision.

Dosage and Administration

The recommended dose should be determined by a healthcare professional based on individual patient requirements and response to therapy. Actose Tablet 15 mg is usually taken once daily, with or without food.

Regular monitoring of blood glucose levels and periodic HbA1c testing are essential to evaluate treatment effectiveness and adjust dosage if necessary.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Safety and Precautions

• Not recommended for patients with Type 1 diabetes or diabetic ketoacidosis.

• Use with caution in patients with a history of heart failure, as fluid retention and edema may occur.

• Liver function tests should be performed before initiating therapy and monitored periodically.

• Weight gain, mild swelling, or anemia may occur in some patients.

• Patients should report symptoms such as rapid weight gain, shortness of breath, or swelling of the legs.

Actose Tablet 15 mg should be used under strict medical supervision. Patients should inform their healthcare provider about any existing medical conditions and concurrent medications before starting treatment.