Colasa Tablet 800 mg contains Mesalazine (5-Aminosalicylic Acid) 800 mg, an effective anti-inflammatory medication used in the treatment and long-term management of inflammatory bowel diseases (IBD), particularly ulcerative colitis. It is formulated to deliver mesalazine directly to the colon, where it reduces inflammation and promotes healing of the intestinal lining.

Ulcerative colitis is a chronic condition characterized by inflammation and ulceration of the colon and rectum. Common symptoms include persistent diarrhea, rectal bleeding, abdominal pain, urgency, and fatigue. Mesalazine is considered a first-line therapy for mild to moderate ulcerative colitis and plays a key role in both active disease treatment and maintenance of remission.

Colasa Tablet 800 mg provides a higher strength option, allowing for flexible dosing and improved convenience for patients who require larger daily doses. By acting locally in the colon, mesalazine minimizes systemic absorption and reduces the likelihood of widespread side effects.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Colasa Tablet 800 mg is indicated for:

• Mild to moderate ulcerative colitis

• Maintenance of remission in ulcerative colitis

• Prevention of relapse in chronic inflammatory bowel disease

• Management of colonic inflammation

Key Benefits

• Effectively reduces intestinal inflammation

• Controls symptoms such as diarrhea, bleeding, and abdominal discomfort

• Supports healing of the colonic mucosa

• Helps maintain long-term remission

• Higher strength tablet reduces pill burden

Mechanism of Action

Mesalazine works by inhibiting the production of inflammatory substances such as prostaglandins and leukotrienes within the intestinal mucosa. It blocks key inflammatory pathways (cyclooxygenase and lipoxygenase), thereby decreasing inflammation and oxidative stress in the colon. This localized anti-inflammatory action helps improve symptoms and prevent disease flare-ups.

Dosage and Administration

The dosage of Colasa Tablet 800 mg should be determined by a physician based on the severity of the condition and individual patient response. It is typically taken in divided doses daily.

Tablets should be swallowed whole with sufficient water and should not be crushed or chewed unless advised. Consistent use as prescribed is essential to achieve optimal therapeutic results and prevent relapse.

Precautions

• Use cautiously in patients with renal or hepatic impairment.

• Regular monitoring of kidney function is recommended during prolonged therapy.

• Inform your healthcare provider about any allergy to salicylates or aspirin.

• Not recommended in severe renal impairment unless strictly supervised.

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Possible Side Effects

Colasa Tablet 800 mg is generally well tolerated. Some patients may experience:

• Nausea

• Abdominal pain

• Headache

• Diarrhea

• Skin rash (rare)

Serious adverse reactions are uncommon but require prompt medical attention.

Storage

Store below 30°C in a cool, dry place. Protect from moisture and direct sunlight. Keep out of reach of children.