Xeldrin Injection 40 mg/vial contains Omeprazole (40 mg), a proton pump inhibitor (PPI) formulated for intravenous use. It is designed for patients who are unable to take oral medications or require rapid acid suppression in hospital settings. This injectable formulation provides effective control of gastric acid secretion, helping to manage serious acid-related conditions and prevent complications.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Active Ingredient

• Omeprazole 40 mg (IV): Omeprazole inhibits the gastric proton pump (H⁺/K⁺ ATPase) in the stomach lining, significantly reducing acid production and promoting healing of the gastrointestinal mucosa.

Indications

Xeldrin Injection 40 mg/vial is primarily indicated for:

• Treatment of severe gastroesophageal reflux disease (GERD)
• Management of peptic ulcers when oral therapy is not feasible
• Prevention and treatment of stress-related mucosal damage in critically ill patients
• Control of upper gastrointestinal bleeding associated with acid-related disorders
• Conditions involving excessive acid secretion such as Zollinger-Ellison syndrome

Mechanism of Action

Omeprazole works by irreversibly blocking the proton pump in gastric parietal cells, which is responsible for the final step of acid production. This results in a rapid and sustained reduction in gastric acid secretion. The intravenous route ensures quick onset of action, making it particularly useful in emergency or hospital settings where immediate acid control is required.

Dosage and Administration

• Administered intravenously by a healthcare professional only
• Typical dose: 40 mg once daily, or as directed by a physician
• The injection should be reconstituted and administered according to standard medical guidelines
• Duration of therapy depends on the patient’s condition and clinical response

Precautions and Warnings

• Should only be used under medical supervision in a clinical setting
• Use with caution in patients with liver impairment
• Long-term use may increase the risk of vitamin B12 deficiency, electrolyte imbalance, or bone fractures
• May mask symptoms of serious gastrointestinal diseases; proper diagnosis is necessary
• Inform the doctor about all concurrent medications to avoid interactions

Possible Side Effects

Xeldrin Injection is generally well-tolerated. Some patients may experience:

• Headache or dizziness
• Injection site reactions such as pain or irritation
• Nausea, diarrhea, or abdominal discomfort
• Rarely, allergic reactions or severe complications

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Storage

• Store in a cool, dry place below 30°C
• Protect from light and moisture
• Keep out of reach of children
• Use immediately after reconstitution as per medical guidelines

Conclusion

Xeldrin Injection 40 mg/vial is an effective intravenous solution for rapid and reliable control of gastric acid secretion in hospitalized patients. It is particularly useful in managing severe acid-related disorders and preventing complications when oral therapy is not possible. With proper medical supervision, it ensures safe and efficient treatment outcomes.