Xadu Tablet 20 mg contains Roxadustat, an innovative oral agent used for the treatment of anemia associated with chronic kidney disease (CKD). Roxadustat belongs to a new therapeutic class known as hypoxia-inducible factor prolyl hydroxylase inhibitors (HIF-PHIs). It is designed to address the underlying causes of CKD-related anemia by stimulating endogenous erythropoietin production and improving iron utilization, offering an effective alternative to traditional injectable erythropoiesis-stimulating agents.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Active ingredient: Roxadustat 20 mg

• Dosage form: Tablet

• Route of administration: Oral

Mechanism of Action

Roxadustat works by inhibiting hypoxia-inducible factor prolyl hydroxylase enzymes, which leads to stabilization of hypoxia-inducible factors (HIFs). This process mimics the body’s natural response to low oxygen levels and results in increased production of endogenous erythropoietin in the kidneys and liver. Additionally, Roxadustat improves iron metabolism by reducing hepcidin levels and enhancing intestinal iron absorption, thereby supporting effective red blood cell production.

Indications

Xadu Tablet 20 mg is indicated for:

• Treatment of anemia in patients with chronic kidney disease

• Management of anemia in both dialysis-dependent and non-dialysis CKD patients, as prescribed

• Improvement of hemoglobin levels and reduction of anemia-related symptoms such as fatigue and weakness

• Supportive therapy where conventional injectable treatments are unsuitable

Dosage and Administration

The dosage of Xadu Tablet 20 mg should be individualized and prescribed by a healthcare professional based on hemoglobin levels, body weight, and clinical response. It is typically taken orally at scheduled intervals. Tablets should be swallowed whole with water and may be taken with or without food. Regular monitoring of hemoglobin and iron parameters is recommended during treatment.

Benefits and Key Features

• Oral treatment option for CKD-related anemia

• Stimulates natural erythropoietin production

• Improves iron utilization and reduces need for intravenous iron

• Helps maintain stable hemoglobin levels

• Convenient dosing improves patient compliance

• Reduces dependence on injectable anemia therapies

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Safety and Precautions

Xadu Tablet 20 mg is generally well tolerated when used under medical supervision. Possible side effects may include headache, nausea, diarrhea, hypertension, or increased potassium levels. Careful monitoring is required to avoid excessive rises in hemoglobin. Caution is advised in patients with cardiovascular disease, liver impairment, or a history of thromboembolic events. Use during pregnancy and breastfeeding should be based strictly on medical advice.

Patients should inform their physician about all ongoing medications and medical conditions before starting therapy.

Storage

Store below 30°C in a dry place, protected from light and moisture. Keep out of reach of children.

Xadu Tablet 20 mg from SK Pharma provides a modern, patient-friendly approach to managing anemia in chronic kidney disease by addressing both erythropoietin deficiency and iron imbalance through advanced oral therapy.