Wilpen Capsule 125 mg contains Penicillamine, a chelating agent and disease-modifying medicine used in the treatment of Wilson’s disease, cystinuria, and certain severe cases of rheumatoid arthritis. It works by binding to heavy metals such as copper and helping remove them from the body through urine. This makes it particularly important in managing Wilson’s disease, a genetic disorder where excessive copper accumulates in the liver, brain, and other organs.

In Wilson’s disease, Penicillamine reduces copper overload and helps prevent liver damage, neurological complications, and other systemic effects. In cystinuria, it helps reduce cystine stone formation in the kidneys. In rheumatoid arthritis, it acts as a second-line disease-modifying antirheumatic drug (DMARD) in patients who do not respond adequately to first-line therapies.

Wilpen Capsule should be used only under strict medical supervision due to its potent effects and need for regular monitoring. Long-term therapy requires periodic blood tests and urine analysis to ensure safety and effectiveness.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

Each capsule contains:

• Penicillamine BP 125 mg

Indications

Wilpen Capsule is indicated for:

• Wilson’s disease (hepatolenticular degeneration)
• Cystinuria (prevention of cystine kidney stones)
• Severe rheumatoid arthritis (as second-line therapy)
• Heavy metal poisoning (copper and other metal chelation)

How It Works

Penicillamine binds to excess copper and other heavy metals in the body, forming stable complexes that are excreted through urine. This reduces toxic accumulation in tissues and helps prevent organ damage.

Dosage and Administration

The dosage should be determined by a registered physician.

• Dose is individualized based on condition, age, and response
• Usually taken on an empty stomach for better absorption
• Treatment requires long-term monitoring of blood counts, kidney function, and urine analysis

Benefits of Wilpen Capsule

• Helps remove excess copper from the body
• Prevents progression of Wilson’s disease complications
• Reduces formation of cystine kidney stones
• Acts as a disease-modifying agent in rheumatoid arthritis
• Supports long-term metabolic and autoimmune management

Precautions

Use cautiously in:

• Kidney impairment
• Bone marrow suppression
• Patients with a history of severe drug reactions
• Pregnancy and breastfeeding (only if clearly necessary)

Regular monitoring of blood cell counts and kidney function is essential during therapy.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Possible Side Effects

Common side effects may include:

• Nausea and vomiting
• Loss of appetite
• Skin rash
• Taste disturbances
• Proteinuria (protein in urine)
• Bone marrow suppression (rare but serious)

Seek immediate medical attention if symptoms such as fever, sore throat, unusual bruising, or severe fatigue occur.

Storage

• Store below 30°C
• Protect from moisture and light
• Keep out of reach of children.