Vistarin Injection 8000 Anti-Xa IU/0.8 ml contains Enoxaparin Sodium, a low molecular weight heparin (LMWH) widely used for prevention and treatment of blood clots. It functions as an anticoagulant by inhibiting Factor Xa and, to a lesser extent, Factor IIa (thrombin), helping to prevent the formation and extension of thrombi.

This higher-dose pre-filled syringe is ideal for patients requiring therapeutic anticoagulation, including those with moderate to high-risk venous thromboembolism, deep vein thrombosis (DVT), pulmonary embolism (PE), or acute coronary syndromes (ACS). Its pre-measured format ensures accurate dosing, convenience, and patient safety.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Vistarin Injection 8000 Anti-Xa IU/0.8 ml is indicated for:

• Prevention of venous thromboembolism (VTE) in high-risk surgical or hospitalized patients
• Treatment of deep vein thrombosis (DVT) with or without pulmonary embolism (PE)
• Management of acute coronary syndromes (ACS) to prevent further thrombus formation
• Therapeutic anticoagulation for patients requiring weight-based dosing or higher anti-Xa activity

Mechanism of Action

Enoxaparin Sodium works by:

• Binding to antithrombin III, enhancing its inhibition of Factor Xa and partially Factor IIa (thrombin)
• Preventing clot formation and propagation in the venous and arterial circulation
• Providing predictable anticoagulant activity with lower risk of heparin-induced thrombocytopenia (HIT) compared to unfractionated heparin
• Reducing the risk of venous and arterial thromboembolic events in patients with cardiovascular or thrombotic disorders

Dosage and Administration

• Administer via subcutaneous injection, typically in the abdomen
• Pre-filled syringe ensures accurate dosing of 8000 Anti-Xa IU/0.8 ml
• Dosage frequency and duration are determined by the patient’s clinical condition, body weight, and physician guidance
• Avoid intramuscular injections to reduce the risk of hematoma
• Rotate injection sites to prevent skin irritation
• Regular monitoring of platelet count, renal function, and signs of bleeding is recommended

Benefits

• Prevents venous thromboembolism and pulmonary embolism in high-risk patients
• Effectively treats deep vein thrombosis and acute coronary syndromes
• Predictable anticoagulant effect reduces the need for frequent laboratory monitoring
• Lower incidence of heparin-induced thrombocytopenia (HIT) than standard heparin
• Pre-filled syringe ensures convenient, accurate, and safe administration

Side Effects

Common side effects may include:

• Mild injection site reactions (pain, redness, swelling)
• Minor bruising or bleeding

Serious but rare side effects:

• Severe internal or gastrointestinal bleeding
• Heparin-induced thrombocytopenia (HIT)
• Allergic reactions, including rash, swelling, or difficulty breathing

Seek immediate medical attention if severe bleeding or allergic reactions occur.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions and Warnings

• Use cautiously in patients with active bleeding, severe renal or hepatic impairment, or thrombocytopenia
• Avoid concurrent use with other anticoagulants or antiplatelet drugs unless prescribed
• Pregnancy and breastfeeding: use only under strict medical supervision
• Regular monitoring of blood counts and coagulation parameters is advised
• Contraindicated in patients with a history of heparin-induced thrombocytopenia (HIT)

Storage

• Store at 2°C to 8°C (refrigerated)
• Protect from light and freezing
• Keep the syringe in its original packaging until use
• Keep out of reach of children
• Do not use after the expiration date.