Vaspine Injection 0.5% + 8% contains Bupivacaine Hydrochloride combined with Dextrose. It is a local anesthetic formulation used mainly for spinal anesthesia (subarachnoid block). This medicine provides effective and long-lasting numbness in the lower part of the body during surgical and diagnostic procedures.

The presence of dextrose makes the solution hyperbaric, allowing better control of anesthetic spread within the spinal fluid.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

Each 5 ml (or as per vial specification) contains:

• Bupivacaine Hydrochloride 0.5%
• Dextrose 8%

Sterile solution for intrathecal (spinal) administration only.

Indications

Vaspine Injection is indicated for:

• Spinal anesthesia in lower abdominal surgery
• Lower limb orthopedic procedures
• Gynecological surgeries
• Urological procedures
• Caesarean section (as directed by anesthesiologist)
• Short to medium duration surgical procedures requiring spinal block

Mechanism of Action

Bupivacaine works by blocking sodium channels in nerve fibers, preventing the transmission of pain signals to the brain. This results in loss of sensation and muscle relaxation in the lower body.

Dextrose increases the density of the solution, making it hyperbaric, which helps anesthesiologists control the spread of anesthesia within the cerebrospinal fluid based on patient positioning.

Dosage and Administration

Vaspine Injection must be administered only by a qualified anesthesiologist.

General guidelines:

• Administered via intrathecal (spinal) injection
• Dose depends on type of surgery, patient condition, and desired duration of anesthesia
• Strict aseptic technique is required
• Continuous monitoring of blood pressure, heart rate, and respiration is essential

Benefits of Vaspine Injection

• Provides effective spinal anesthesia
• Rapid onset of action
• Long duration of pain relief
• Allows controlled spread of anesthesia
• Reduces need for general anesthesia in suitable cases

Possible Side Effects

Some patients may experience:

• Low blood pressure (hypotension)
• Nausea or vomiting
• Headache after spinal anesthesia
• Backache
• Temporary urinary retention
• Dizziness

Rare but serious side effects include:

• High spinal block
• Allergic reactions
• Cardiac or respiratory depression
• Neurological complications (very rare)

Precautions and Warnings

• Must be administered only by trained anesthesiologist
• Continuous monitoring is required during procedure
• Use cautiously in patients with heart or liver disease
• Avoid in patients with infection at injection site
• Emergency resuscitation equipment must be available

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Storage Instructions

• Store below 25°C
• Protect from light
• Do not freeze
• Use only under sterile conditions
• Keep out of reach of children

Conclusion

Vaspine Injection 0.5% + 8% (Bupivacaine Hydrochloride + Dextrose) is a spinal anesthetic used to provide effective and controlled numbness during surgical procedures. It ensures reliable pain relief and muscle relaxation when administered by a qualified anesthesiologist under strict medical supervision.