Vasolax Tablet 400 mg contains Pentoxifylline 400 mg, a hemorheologic agent used to improve blood flow in patients with impaired circulation. It is primarily prescribed for the management of peripheral vascular diseases, particularly conditions associated with reduced blood flow to the limbs. By improving the flexibility of red blood cells and reducing blood viscosity, Vasolax Tablet enhances microcirculation and oxygen delivery to tissues, helping relieve symptoms caused by poor circulation.

Pentoxifylline is especially beneficial in patients suffering from intermittent claudication, a condition characterized by pain, cramping, or weakness in the legs during walking due to insufficient blood supply. Regular use of Vasolax Tablet can improve walking distance, reduce pain, and enhance overall mobility and quality of life.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Vasolax Tablet 400 mg is indicated for the treatment of:

• Peripheral arterial disease

• Intermittent claudication associated with chronic occlusive arterial disease

• Circulatory disorders due to impaired blood flow

• Conditions where improvement of microcirculation is required

Therapeutic Class

• Hemorheologic agent

• Peripheral vasodilator

Pharmacology

Pentoxifylline is a methylxanthine derivative that acts by improving blood rheology. It increases the deformability of red blood cells, reduces platelet aggregation, and decreases blood viscosity. These effects lead to enhanced blood flow through narrowed or obstructed blood vessels. Pentoxifylline also improves tissue oxygenation and reduces inflammation at the microvascular level. Unlike direct vasodilators, it does not significantly alter blood pressure, making it suitable for long-term use in patients with vascular disorders.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Dosage & Administration

• The usual recommended dose is 400 mg two to three times daily, or as directed by a physician

• Tablets should be taken with meals to reduce gastrointestinal discomfort

• The tablet should be swallowed whole and not crushed or chewed

• Dosage adjustment may be necessary in elderly patients or those with renal impairment

Drug Interactions

• Increased risk of bleeding when used with anticoagulants or antiplatelet agents

• Enhanced hypotensive effect with antihypertensive medications

• Increased pentoxifylline levels when used with theophylline

• Caution is advised when used with drugs affecting blood coagulation

Contraindications

• Hypersensitivity to pentoxifylline or other methylxanthines

• Recent cerebral or retinal hemorrhage

• Acute myocardial infarction

• Severe bleeding disorders

Side Effects

Common side effects include nausea, vomiting, abdominal discomfort, dizziness, headache, and flushing. Less frequent adverse effects may include palpitations, hypotension, sleep disturbances, and skin rash. Rarely, bleeding complications or hypersensitivity reactions may occur. Most side effects are mild to moderate and resolve with continued therapy or dose adjustment.

Precautions & Warnings

• Use with caution in patients with bleeding risk or peptic ulcer disease

• Close monitoring is advised in patients taking anticoagulants

• Caution in elderly patients and those with renal or hepatic impairment

• Discontinue use and consult a physician if severe adverse reactions occur

Storage Conditions

• Store below 30°C

• Keep in a dry place, protected from light

• Keep out of reach of children.