Turboclav Suspension (125 mg + 31.25 mg)/5 ml is an oral antibiotic formulation containing Cefuroxime Axetil and Clavulanic Acid. This combination is specially designed to provide effective antibacterial therapy in pediatric patients and in adults who have difficulty swallowing tablets. By combining a second-generation cephalosporin with a beta-lactamase inhibitor, Turboclav Suspension offers broad-spectrum activity against a wide range of bacterial pathogens, including beta-lactamase-producing strains.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

Each 5 ml of reconstituted suspension contains:

• Cefuroxime Axetil 125 mg

• Clavulanic Acid 31.25 mg

Therapeutic Class

• Cephalosporin antibiotic with beta-lactamase inhibitor

Indications

Turboclav Suspension is indicated for the treatment of mild to moderate bacterial infections caused by susceptible organisms, including:

• Upper and lower respiratory tract infections such as sinusitis, pharyngitis, tonsillitis, bronchitis, and pneumonia

• Ear infections including otitis media

• Urinary tract infections

• Skin and soft tissue infections

• Dental and odontogenic infections

It is particularly suitable for children due to its palatable suspension form and flexible dosing.

Pharmacology

Cefuroxime Axetil is a prodrug that is converted into its active form, cefuroxime, after oral administration. Cefuroxime inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins, resulting in bacterial cell death.
Clavulanic Acid acts by inhibiting beta-lactamase enzymes produced by resistant bacteria, thereby protecting cefuroxime from degradation. This combination enhances the antimicrobial spectrum and improves effectiveness against resistant organisms.

Dosage and Administration

The dosage of Turboclav Suspension should be determined by a healthcare professional based on the patient’s age, body weight, severity of infection, and renal function. The suspension should be taken orally, preferably after meals, to improve absorption and reduce gastrointestinal discomfort. Shake the bottle well before each use. The full course of therapy should be completed even if symptoms improve earlier.

Contraindications

• Hypersensitivity to cefuroxime, clavulanic acid, cephalosporins, or other beta-lactam antibiotics

• History of severe allergic reactions to penicillins or cephalosporins

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions and Warnings

• Use with caution in patients with renal impairment

• Prolonged use may lead to superinfection with non-susceptible organisms

• Patients with a history of gastrointestinal disease should be monitored carefully

• Use during pregnancy and breastfeeding only when clearly indicated and under medical advice

Adverse Effects

Common side effects may include:

• Diarrhea, nausea, vomiting

• Abdominal discomfort

• Skin rash or mild allergic reactions

Rare but serious adverse effects include hypersensitivity reactions and changes in liver enzyme levels.

Storage

Before reconstitution, store in a cool, dry place below 30°C. After reconstitution, store as directed by the manufacturer and use within the recommended time period. Keep out of reach of children.