Trexam Injection 500 mg/5 ml contains Tranexamic Acid, an antifibrinolytic agent used to control and prevent excessive bleeding in various medical conditions. It works by stabilizing blood clots and reducing the breakdown of fibrin, thereby helping to minimize blood loss.

This injectable form is commonly used in hospital and emergency settings, especially when rapid control of bleeding is required or when oral administration is not suitable.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

Each 5 ml ampoule contains:

• Tranexamic Acid 500 mg

Available as a sterile solution for intravenous administration.

Indications

Trexam Injection 500 mg/5 ml is indicated for:

• Post-surgical bleeding control
• Heavy menstrual bleeding (when oral therapy is not suitable)
• Trauma-related bleeding
• Epistaxis (severe nosebleeds)
• Dental bleeding after surgical procedures
• Obstetric and gynecological bleeding (under supervision)
• Bleeding due to increased fibrinolysis in medical conditions

Mechanism of Action

Tranexamic Acid works by blocking the activation of plasminogen into plasmin, an enzyme responsible for breaking down fibrin clots. By inhibiting this process, it prevents premature clot breakdown and helps maintain hemostasis (control of bleeding).

This results in reduced blood loss and improved clot stability in bleeding conditions.

Dosage and Administration

Trexam Injection should be administered only by a qualified healthcare professional.

General guidelines:

• Given via slow intravenous injection or infusion
• Dose depends on the severity and type of bleeding
• Must be administered under strict medical supervision
• Treatment duration is determined by the physician

Rapid injection should be avoided to reduce the risk of adverse effects.

Benefits of Trexam Injection

• Rapid control of acute bleeding
• Stabilizes blood clots effectively
• Useful in emergency and surgical settings
• Reduces need for blood transfusion in some cases
• Effective when oral therapy is not possible

Possible Side Effects

Some patients may experience:

• Nausea or vomiting
• Dizziness
• Diarrhea
• Injection site reactions
• Headache

Rare but serious side effects include:

• Thromboembolic events (blood clots)
• Visual disturbances
• Hypotension (if injected too rapidly)
• Allergic reactions

Immediate medical attention is required if symptoms of clot formation occur.

Precautions and Warnings

• Use cautiously in patients with a history of thrombosis
• Not recommended in active blood clot disorders
• Adjust dose in kidney impairment
• Administer slowly to avoid hypotension
• Avoid long-term unsupervised use
• Inform the physician about all medications and medical history

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Storage Instructions

• Store below 25°C
• Protect from light
• Do not freeze
• Keep out of reach of children
• Use immediately after opening as directed

Conclusion

Trexam Injection 500 mg/5 ml (Tranexamic Acid) is an effective antifibrinolytic medicine used for rapid control of bleeding in surgical, traumatic, and gynecological conditions. By stabilizing blood clots and reducing fibrinolysis, it helps prevent excessive blood loss and supports patient recovery in emergency situations. Proper medical supervision is essential for safe and effective use.