Sofomax Tablet 400 mg contains Sofosbuvir, a direct-acting antiviral (DAA) used in the treatment of chronic hepatitis C virus (HCV) infection. It works by inhibiting the viral RNA polymerase, preventing the replication of the virus in the liver.

Sofomax is highly effective in clearing HCV from the bloodstream, improving liver function, and reducing the risk of cirrhosis and liver-related complications. It is often used in combination with other antiviral agents for optimized treatment outcomes across multiple HCV genotypes.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Sofosbuvir 400 mg per tablet

Mechanism of Action

• Sofosbuvir is a nucleotide analog inhibitor of HCV NS5B RNA-dependent RNA polymerase.
• It is incorporated into viral RNA during replication, resulting in chain termination and halting viral proliferation.
• By blocking viral replication, Sofosbuvir allows the immune system to clear infected liver cells.
• Offers high efficacy across HCV genotypes and has a favorable safety profile.

Indications

Sofomax Tablet 400 mg is indicated for:

• Chronic hepatitis C virus (HCV) infection in adults
• Used in combination with ribavirin, peginterferon, or other DAAs depending on genotype and treatment history
• Patients with compensated liver disease, including cirrhosis (Child-Pugh A)
• Suitable for treatment-naïve and previously treated patients

Dosage & Administration

• Typical dosage: 400 mg once daily, with or without food, as prescribed by a physician
• Duration depends on HCV genotype, liver condition, and previous treatment history, typically 12–24 weeks
• Combination with other antiviral medications may be required for optimal results
• Adherence to the prescribed regimen is critical for achieving sustained virologic response (SVR)

Benefits

• Highly effective in achieving viral clearance
• Reduces liver inflammation and fibrosis progression
• Convenient once-daily oral dosing
• Minimal drug interactions and well-tolerated
• Improves overall liver health and reduces risk of cirrhosis or liver cancer

Possible Side Effects

Common side effects:

• Fatigue
• Headache
• Nausea
• Insomnia

Less common but serious side effects:

• Anemia (usually when combined with ribavirin)
• Severe allergic reactions (rare)
• Liver enzyme elevations in patients with pre-existing liver disease

Precautions & Warnings

• Not recommended in patients with severe hepatic impairment (Child-Pugh C) without specialist supervision
• Pregnancy and breastfeeding: consult a physician; ribavirin co-administration is contraindicated in pregnancy
• Inform your doctor about all other medications to avoid potential interactions
• Regular liver function tests and viral load monitoring are advised

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Storage

• Store at 20–25°C in a dry, cool place
• Protect from moisture, light, and heat
• Keep out of reach of children

Conclusion

Sofomax Tablet 400 mg (Sofosbuvir) is a highly effective antiviral therapy for chronic hepatitis C. It inhibits viral replication, supports liver health, and provides a well-tolerated, once-daily oral treatment for adults across multiple HCV genotypes.