Sodival CR Tablet 200 mg contains Sodium Valproate, an anticonvulsant and mood-stabilizing agent widely used to manage epilepsy, bipolar disorder, and seizure disorders. The controlled-release (CR) formulation ensures a steady release of the active ingredient, allowing once or twice-daily dosing for better symptom control and improved patient compliance.

Sodival CR helps reduce the frequency and severity of seizures, while also stabilizing mood swings in patients with bipolar disorder, offering a reliable solution for long-term management of neurological and psychiatric conditions.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Sodium Valproate 200 mg per controlled-release tablet

Mechanism of Action

• Sodium Valproate increases gamma-aminobutyric acid (GABA) levels in the brain, an inhibitory neurotransmitter that calms excessive electrical activity in neurons.
• Reduces neuronal excitability, preventing seizure propagation.
• Stabilizes mood by modulating neurotransmitter activity involved in emotional regulation.
• The CR formulation ensures consistent blood levels of Sodium Valproate, reducing peaks and troughs and minimizing side effects.

Indications

Sodival CR Tablet 200 mg is indicated for:

• Epilepsy: generalized, partial, or mixed seizure types
• Bipolar disorder: as a mood stabilizer for manic and mixed episodes
• Prevention of migraine attacks in patients with frequent migraine headaches (off-label in some cases)
• Other neurological disorders where GABAergic modulation is beneficial

Dosage & Administration

• Take as prescribed by a physician
• The tablet should be swallowed whole with water, preferably with food to minimize gastrointestinal discomfort
• Usual starting dose for adults: 200–400 mg once or twice daily, adjusted based on clinical response and serum levels
• Dose adjustments are required for children, elderly, and patients with liver impairment
• Do not crush or chew the CR tablet, as it affects the controlled-release mechanism

Benefits

• Reduces frequency and severity of seizures
• Stabilizes mood swings in bipolar disorder
• Controlled-release formulation ensures stable blood levels
• Convenient once or twice-daily dosing improves compliance
• Supports long-term neurological and psychiatric health

Possible Side Effects

Common side effects:

• Nausea, vomiting, or mild gastrointestinal discomfort
• Drowsiness, dizziness, or tremors
• Weight gain or increased appetite
• Hair thinning (temporary)

Serious side effects (rare):

• Liver toxicity or elevated liver enzymes
• Pancreatitis
• Severe allergic reactions (rash, swelling, or difficulty breathing)
• Blood disorders (thrombocytopenia, leukopenia)

Precautions & Warnings

• Monitor liver function and blood counts regularly during therapy
• Not recommended in patients with known liver disease or urea cycle disorders
• Use caution during pregnancy, as Sodium Valproate may cause fetal malformations
• Avoid abrupt discontinuation to prevent seizure recurrence
• Consult a physician before combining with other medications

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Storage

• Store at 20–25°C in a dry, cool place
• Keep the tablet in its original container
• Protect from moisture, light, and heat
• Keep out of reach of children

Conclusion

Sodival CR Tablet 200 mg (Sodium Valproate) is an effective anticonvulsant and mood stabilizer. Its controlled-release formulation provides consistent therapeutic levels, reduces seizure frequency, and supports mood stabilization in bipolar disorder, making it a trusted option for long-term neurological and psychiatric management.