Sinjard-M Tablet 12.5 mg+500 mg is a combination oral antidiabetic medicine containing Empagliflozin and Metformin Hydrochloride. It is used in the management of type 2 diabetes mellitus when blood glucose levels are not adequately controlled by diet, exercise, or monotherapy. This combination provides dual mechanisms of action to improve glycemic control effectively and support long-term diabetes management.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Empagliflozin 12.5 mg
• Metformin Hydrochloride 500 mg

Mechanism of Action

Sinjard-M Tablet works through two complementary mechanisms to reduce blood glucose levels:

• Empagliflozin: An SGLT2 inhibitor that lowers blood glucose by preventing reabsorption of glucose in the kidneys, increasing its excretion through urine.
• Metformin Hydrochloride: A biguanide that reduces hepatic glucose production, decreases intestinal absorption of glucose, and improves insulin sensitivity in peripheral tissues.

This combination provides synergistic glucose-lowering effects with added metabolic benefits.

Indications

Sinjard-M Tablet is indicated for:

• Management of type 2 diabetes mellitus in adults
• Patients inadequately controlled on metformin alone or other antidiabetic therapies
• Combination therapy along with diet and exercise for improved glycemic control

Dosage and Administration

• The dosage should be determined by a physician based on patient condition.
• Usually taken once or twice daily with meals to minimize gastrointestinal side effects.
• Swallow the tablet whole with water.
• Regular monitoring of blood glucose levels is recommended during treatment.

Benefits

• Dual-action therapy for improved blood sugar control
• Helps reduce fasting and postprandial glucose levels
• Supports weight management through glucose excretion
• Improves insulin sensitivity and metabolic control
• May provide cardiovascular and renal protective benefits

Side Effects

Common side effects may include:

• Nausea or vomiting
• Diarrhea
• Abdominal discomfort
• Increased urination
• Urinary tract or genital infections

Rare but serious side effects include lactic acidosis (associated with Metformin), ketoacidosis, and dehydration. Immediate medical attention is required if severe symptoms occur.

Precautions and Warnings

• Not recommended for type 1 diabetes or diabetic ketoacidosis.
• Use with caution in patients with kidney or liver impairment.
• Avoid excessive alcohol consumption due to risk of lactic acidosis.
• Maintain adequate hydration during therapy.
• Regular monitoring of renal function and blood glucose is advised.
• Consult a physician if pregnant or breastfeeding.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Drug Interactions

Sinjard-M Tablet may interact with:

• Diuretics (increased risk of dehydration)
• Insulin or other antidiabetic agents (risk of hypoglycemia)
• Alcohol (increased risk of lactic acidosis)
• Certain antihypertensive drugs

Always inform your healthcare provider about all medications being used.

Storage

• Store below 30°C in a cool, dry place
• Protect from moisture and direct sunlight
• Keep out of reach of children.