Raditrend Tablet 6.25 mg contains Carvedilol 6.25 mg, a non-selective beta-blocker with additional alpha-1 blocking activity. It is commonly used in the management of high blood pressure, heart failure, and certain heart-related conditions. Carvedilol helps improve heart function and reduce cardiovascular risk by lowering heart rate and blood pressure.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Raditrend 6.25 mg is indicated for:

• Hypertension (high blood pressure)

• Chronic heart failure

• Left ventricular dysfunction following myocardial infarction

• Angina (in some cases, as prescribed)

It may be used alone or in combination with other antihypertensive or heart failure medications.

Mechanism of Action

Carvedilol works through dual mechanisms:

• Beta-blocking action (β1 and β2 receptors):

  • Reduces heart rate

  • Decreases myocardial contractility

  • Lowers oxygen demand of the heart

• Alpha-1 blocking action:

  • Causes vasodilation (widening of blood vessels)

  • Reduces peripheral vascular resistance

  • Lowers blood pressure

This combined effect improves cardiac output and reduces workload on the heart.

Dosage and Administration

• The usual starting dose for heart failure is 6.25 mg twice daily, depending on patient condition.

• For hypertension, dosing may vary based on physician recommendation.

• Take with food to reduce the risk of orthostatic hypotension.

• Dose may be gradually increased under medical supervision.

Do not stop the medication abruptly; gradual tapering is recommended.

Benefits

• Effectively lowers blood pressure

• Improves symptoms of heart failure

• Reduces risk of hospitalization in heart failure patients

• Protects heart after myocardial infarction

• Long-term cardiovascular risk reduction

Side Effects

Common side effects:

• Dizziness

• Fatigue

• Low blood pressure

• Slow heart rate (bradycardia)

• Weight gain (in heart failure patients)

Serious but less common:

• Severe hypotension

• Worsening heart failure (initially)

• Bronchospasm (in asthma patients)

• Severe allergic reactions

Seek immediate medical attention if severe dizziness, fainting, breathing difficulty, or swelling occurs.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions and Warnings

• Use cautiously in patients with asthma or chronic obstructive pulmonary disease (COPD).

• Monitor heart rate and blood pressure regularly.

• Use caution in diabetic patients (may mask hypoglycemia symptoms).

• Avoid abrupt discontinuation.

• Use cautiously in liver impairment.

Contraindications

• Severe bradycardia

• Cardiogenic shock

• Severe liver impairment

• Uncontrolled heart failure requiring IV therapy

• Hypersensitivity to carvedilol

Storage

Store below 30°C in a dry place, protected from light and moisture. Keep out of reach of children.