Radimet Tablet 500 mg contains Metformin Hydrochloride 500 mg, an oral antidiabetic medication widely used as a first-line treatment for type 2 diabetes mellitus. It belongs to the biguanide class and helps control blood glucose levels by improving the body’s response to insulin and reducing glucose production in the liver.

Metformin is one of the most commonly prescribed and well-established medications for diabetes management worldwide.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Radimet 500 mg is indicated for:

• Management of type 2 diabetes mellitus

• Overweight or obese diabetic patients

• Use as monotherapy when diet and exercise are insufficient

• Combination therapy with:

  • Sulfonylureas

  • DPP-4 inhibitors

  • Insulin

  • SGLT2 inhibitors

It may also be used in certain cases of insulin resistance, as determined by a physician.

It is not indicated for type 1 diabetes or diabetic ketoacidosis.

Mechanism of Action

Metformin works through multiple mechanisms:

• Decreases hepatic glucose production (gluconeogenesis)

• Improves insulin sensitivity in muscle and fat tissues

• Enhances peripheral glucose uptake

• Reduces intestinal glucose absorption

Unlike some other antidiabetic drugs, metformin does not stimulate insulin secretion, which reduces the risk of hypoglycemia when used alone.

Dosage and Administration

• The usual starting dose is 500 mg once or twice daily, taken with meals.

• Dose may be gradually increased based on blood glucose response and tolerability.

• Maximum daily dose varies according to medical guidance.

Taking the tablet with food helps reduce gastrointestinal side effects. Swallow the tablet whole with water.

Renal function should be evaluated before starting therapy and monitored regularly.

Benefits

• First-line treatment for type 2 diabetes

• Effective reduction in fasting and post-meal blood glucose

• Helps lower HbA1c levels

• Weight-neutral or modest weight loss effect

• Low risk of hypoglycemia when used alone

• May reduce cardiovascular risk in diabetic patients

Side Effects

Common side effects:

• Nausea

• Diarrhea

• Abdominal discomfort

• Loss of appetite

• Metallic taste

Serious but rare side effect:

• Lactic acidosis (a rare but potentially serious condition)

Seek immediate medical attention if symptoms such as muscle pain, difficulty breathing, severe weakness, or unusual drowsiness occur.

Precautions and Warnings

• Contraindicated in severe renal impairment.

• Use caution in patients with liver disease or heart failure.

• Temporarily discontinue before iodinated contrast imaging procedures.

• Avoid excessive alcohol consumption.

• Monitor kidney function regularly.

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Contraindications

• Severe renal impairment

• Metabolic acidosis, including diabetic ketoacidosis

• Hypersensitivity to metformin or any component of the formulation

Storage

Store below 30°C in a dry place, protected from light and moisture. Keep out of reach of children.