Posac Tablet 100 mg contains Posaconazole, a broad-spectrum antifungal agent used to prevent and treat serious fungal infections. It belongs to the triazole class of antifungals and is effective against Candida species, Aspergillus species, and other pathogenic fungi. Posac is commonly prescribed for immunocompromised patients, including those undergoing chemotherapy, hematopoietic stem cell transplantation, or with prolonged neutropenia, to reduce the risk of invasive fungal infections.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

Each tablet contains:

• Posaconazole 100 mg

Mechanism of Action

Posaconazole works by inhibiting the fungal enzyme lanosterol 14α-demethylase, which is essential for ergosterol synthesis:

• Blocks the production of ergosterol, a key component of fungal cell membranes
• Disrupts cell membrane integrity, leading to fungal cell death
• Provides broad-spectrum antifungal activity against yeasts and molds
• Prevents proliferation of pathogenic fungi in high-risk patients

Indications

Posac Tablet is indicated for:

• Prevention of invasive fungal infections in immunocompromised patients
• Treatment of oropharyngeal and esophageal candidiasis
• Management of invasive aspergillosis and other systemic fungal infections
• Patients at high risk of fungal infections due to chemotherapy, transplant, or prolonged neutropenia

Dosage and Administration

• Take as prescribed by a healthcare professional.
• Usually administered orally with food to improve absorption.
• Dosage and duration depend on the type and severity of infection.
• Swallow the tablet whole; do not crush or chew.
• Monitor liver function during prolonged therapy.

Benefits

• Broad-spectrum antifungal coverage
• Effective for prevention and treatment of systemic fungal infections
• Supports high-risk patients with compromised immune systems
• Convenient oral tablet formulation
• Reduces morbidity and mortality from invasive fungal infections

Side Effects

Common side effects may include:

• Nausea and vomiting
• Diarrhea
• Headache
• Abdominal pain

Serious side effects, though rare, may include:

• Liver enzyme elevation or hepatotoxicity
• QT interval prolongation
• Allergic reactions or rash

Consult a physician if severe or persistent side effects occur.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions

• Use with caution in patients with liver impairment.
• Monitor for drug interactions, especially with other antifungals or medications affecting liver enzymes.
• Avoid use in patients with known hypersensitivity to azole antifungals.
• Not recommended during pregnancy or breastfeeding without medical supervision.
• Regular blood work may be required during prolonged treatment.

Storage

• Store at room temperature below 25°C
• Keep in a dry, cool place away from light
• Keep out of reach of children.