Polycef Capsule 500 mg contains Cephradine, a first-generation cephalosporin antibiotic used to treat a variety of bacterial infections. Cephradine works by inhibiting the synthesis of bacterial cell walls, causing the death of susceptible bacteria. It is effective against gram-positive bacteria and some gram-negative bacteria, making it suitable for managing respiratory tract infections, skin and soft tissue infections, urinary tract infections, and bone infections.

Polycef 500 mg offers a higher-dose formulation for adults, ensuring adequate therapeutic levels in the bloodstream to combat moderate to severe bacterial infections. Its oral capsule form provides convenient administration and precise dosing for optimal treatment outcomes.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Key Features

• Contains Cephradine 500 mg per capsule

• First-generation cephalosporin antibiotic

• Treats a broad spectrum of bacterial infections

• Oral capsule for easy and accurate dosing

• Effective against gram-positive and certain gram-negative bacteria

• Supports recovery from mild to moderate bacterial infections

Indications

Polycef Capsule 500 mg is indicated for:

• Respiratory tract infections: Bronchitis, pneumonia, pharyngitis, and tonsillitis caused by susceptible bacteria

• Skin and soft tissue infections: Cellulitis, abscesses, wounds, and other soft tissue infections

• Urinary tract infections: Cystitis, urethritis, and pyelonephritis

• Bone infections: Osteomyelitis caused by susceptible bacteria

• Other bacterial infections: As guided by culture and sensitivity tests

Mechanism of Action

Cephradine, the active ingredient, works by:

• Binding to penicillin-binding proteins (PBPs) on bacterial cell walls

• Inhibiting cell wall synthesis, leading to bacterial lysis and death

• Targeting actively dividing bacteria, making it highly effective against infections

This mechanism ensures rapid elimination of bacterial pathogens while minimizing the risk of resistance when used appropriately.

Dosage and Administration

• Typical adult dose: 500 mg orally every 6–12 hours, depending on the infection and severity

• Children’s dose is calculated based on body weight

• Swallow capsules with a full glass of water

• Take the full prescribed course even if symptoms improve, to prevent recurrence and resistance

• Can be taken with or without food; taking with food may reduce stomach discomfort

Possible Side Effects

Common side effects:

• Nausea, vomiting, or diarrhea

• Abdominal discomfort or pain

• Rash or mild allergic reactions

• Headache or dizziness

Serious but rare side effects:

• Severe allergic reactions, including anaphylaxis

• Clostridium difficile-associated diarrhea

• Liver or kidney function abnormalities

• Blood disorders such as leukopenia or thrombocytopenia

Patients should seek immediate medical attention if they experience severe reactions, persistent diarrhea, or unusual bleeding.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions

• Use only under medical supervision

• Inform your doctor of any allergies, especially to penicillin or cephalosporins

• Adjust dosage in patients with kidney impairment

• Avoid unnecessary antibiotic use to reduce resistance

• Consult a physician if pregnant or breastfeeding

Storage Instructions

• Store in a cool, dry place below 25°C

• Protect from light and moisture

• Keep capsules in the original container, tightly closed

• Keep out of reach of children.