Pegalin Capsule 50 mg contains Pregabalin, a centrally acting neuromodulator used in the treatment of neuropathic pain, epilepsy, and generalized anxiety disorder. It works by stabilizing overactive nerve activity in the central nervous system, helping to reduce pain signals, calm nerve excitability, and improve overall neurological comfort.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Pregabalin 50 mg

Indications

Pegalin Capsule is indicated for:

• Neuropathic pain (diabetic neuropathy, post-herpetic neuralgia)
• Fibromyalgia
• Adjunct therapy for partial seizures (epilepsy)
• Generalized anxiety disorder (GAD)
• Neuropathic pain due to spinal cord injury

Mechanism of Action

Pregabalin binds to the alpha-2-delta subunit of voltage-gated calcium channels in the central nervous system. This reduces the release of excitatory neurotransmitters such as glutamate, norepinephrine, and substance P, leading to decreased neuronal excitability and relief from neuropathic pain, anxiety, and seizure activity.

Dosage and Administration

• Dosage is individualized based on medical condition and response to therapy.
• Commonly taken 1–2 times daily or as prescribed by a physician.
• Swallow whole with water, with or without food.
• Do not discontinue suddenly without medical advice.

Benefits

• Effective relief from nerve-related (neuropathic) pain
• Reduces burning, tingling, and shooting pain sensations
• Helps manage generalized anxiety symptoms
• Improves sleep quality in chronic pain conditions
• Supports seizure control as adjunct therapy

Side Effects

Pegalin Capsule may cause:

• Drowsiness or dizziness
• Blurred vision
• Weight gain
• Dry mouth
• Difficulty concentrating
• Swelling in extremities (rare)

Most side effects are mild and improve with continued use.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions and Warnings

• May cause dizziness; avoid driving or operating machinery.
• Use with caution in patients with kidney impairment (dose adjustment required).
• Do not stop abruptly; taper gradually under medical supervision.
• Avoid alcohol during treatment.
• Use only under physician guidance.

Storage

• Store below 30°C
• Protect from moisture and light
• Keep out of reach of children.