Pegalin Capsule 100 mg contains Pregabalin, a centrally acting neuromodulator used for the treatment of neuropathic pain, epilepsy, and generalized anxiety disorder. It helps reduce abnormal nerve activity in the brain and spinal cord, thereby relieving pain, calming nerve excitability, and improving overall neurological function. This higher-strength formulation is used in patients requiring more effective control of moderate to severe neuropathic conditions.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Pregabalin 100 mg

Indications

Pegalin Capsule is indicated for:

• Neuropathic pain (diabetic neuropathy, post-herpetic neuralgia)
• Fibromyalgia
• Adjunct therapy for partial seizures (epilepsy)
• Generalized anxiety disorder (GAD)
• Neuropathic pain associated with spinal cord injury

Mechanism of Action

Pregabalin binds to the alpha-2-delta subunit of voltage-gated calcium channels in the central nervous system. This reduces the release of excitatory neurotransmitters such as glutamate, norepinephrine, and substance P, leading to decreased neuronal excitability and effective relief from neuropathic pain, anxiety, and seizure activity.

Dosage and Administration

• Dosage is individualized based on patient condition and response to treatment.
• Usually taken 1–2 times daily or as prescribed by a physician.
• Swallow whole with water, with or without food.
• Do not discontinue abruptly; gradual dose reduction may be required.

Benefits

• Effective relief from moderate to severe neuropathic pain
• Reduces burning, tingling, and shooting nerve pain
• Helps control generalized anxiety symptoms
• Improves sleep quality in chronic pain patients
• Supports adjunct therapy in seizure management

Side Effects

Pegalin Capsule may cause:

• Drowsiness or dizziness
• Blurred vision
• Weight gain
• Dry mouth
• Difficulty concentrating
• Peripheral edema (rare)

Most side effects are mild and usually improve with continued use.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions and Warnings

• May cause dizziness; avoid driving or operating machinery.
• Use caution in patients with kidney impairment (dose adjustment required).
• Do not stop suddenly; tapering is necessary under medical supervision.
• Avoid alcohol during treatment.
• Use only under physician guidance.

Storage

• Store below 30°C
• Protect from moisture and light
• Keep out of reach of children.