Pcab Tablet 20 mg contains Vonoprazan, a potent potassium-competitive acid blocker (P-CAB) used for the treatment of gastroesophageal reflux disease (GERD), peptic ulcers, and Helicobacter pylori infections. Vonoprazan works by inhibiting the final step of gastric acid secretion, providing rapid, potent, and long-lasting acid suppression.

Compared to conventional proton pump inhibitors (PPIs), Vonoprazan offers faster onset of action, more consistent acid control, and enhanced healing of acid-related gastrointestinal lesions. The higher 20 mg dose is typically prescribed for patients requiring stronger acid suppression, including severe GERD or ulcer cases, and as part of combination therapy for H. pylori eradication.

Pcab Tablet 20 mg ensures convenient oral administration and accurate dosing under medical supervision, making it an effective solution for managing acid-related gastrointestinal conditions.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Key Features

• Contains Vonoprazan 20 mg per tablet

• Potent potassium-competitive acid blocker for fast and sustained acid suppression

• Treats GERD, peptic ulcers, and H. pylori-associated gastrointestinal disorders

• Oral tablet formulation for convenient once-daily administration

• Higher dose for severe or resistant acid-related conditions

• Can be used in combination therapy for H. pylori eradication

Indications

Pcab Tablet 20 mg is indicated for:

• Severe GERD: Relief of heartburn, acid reflux, and esophagitis

• Peptic ulcers: Accelerates healing of gastric and duodenal ulcers

• H. pylori eradication: Part of combination therapy with antibiotics for H. pylori-associated ulcers

• Prevention of NSAID-induced ulcers: In patients at high risk for gastrointestinal bleeding due to long-term NSAID use

Treatment should always be guided by a physician based on the patient’s condition and severity.

Mechanism of Action

Vonoprazan selectively blocks gastric acid secretion by:

• Inhibiting potassium ions at the H+/K+-ATPase (proton pumps) in gastric parietal cells

• Preventing the final step of acid production more effectively than PPIs

• Providing rapid and sustained acid suppression throughout day and night

This mechanism ensures effective symptom relief, faster ulcer healing, and better overall management of acid-related gastrointestinal disorders.

Dosage and Administration

• Standard adult dose: 20 mg orally once daily, usually before a meal

• Swallow tablets whole with water; do not crush or chew

• Duration of therapy varies by condition:

  • GERD: 4–8 weeks, with possible continuation for maintenance

  • Peptic ulcer: 4–6 weeks

  • H. pylori eradication: Used in combination therapy with antibiotics as prescribed

• Follow the prescribing physician’s instructions for dose and duration

Possible Side Effects

Common side effects may include:

• Headache

• Diarrhea or constipation

• Nausea or vomiting

• Abdominal discomfort or bloating

• Mild dizziness

Rare but serious side effects:

• Liver function abnormalities

• Severe gastrointestinal disturbances

• Allergic reactions

Patients should report severe or persistent symptoms to their healthcare provider immediately.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions

• Use under medical supervision, especially in patients with liver impairment

• Avoid long-term self-medication

• Inform your doctor of all medications to prevent interactions

• Not recommended during pregnancy or breastfeeding unless prescribed

• Regular monitoring may be required for long-term therapy

Storage Instructions

• Store in a cool, dry place below 25°C

• Protect from light and moisture

• Keep tablets in the original container, tightly closed

• Keep out of reach of children.