Paloxi ODT Tablet 0.5 mg contains Palonosetron, a second-generation serotonin (5-HT3) receptor antagonist used for the prevention of nausea and vomiting. This orally disintegrating tablet (ODT) formulation dissolves quickly in the mouth without the need for water, making it convenient for patients undergoing chemotherapy, radiotherapy, or surgical procedures.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Active Ingredient: Palonosetron Hydrochloride
• Strength: 0.5 mg per ODT tablet

Mechanism of Action

Palonosetron works by selectively blocking 5-HT3 receptors found in the central nervous system and gastrointestinal tract. These receptors are responsible for triggering nausea and vomiting reflexes during chemotherapy, radiotherapy, and postoperative recovery. By inhibiting these receptors, Palonosetron provides effective protection against both acute and delayed emesis.

Indications

Paloxi ODT Tablet 0.5 mg is indicated for:

• Prevention of chemotherapy-induced nausea and vomiting (CINV)
• Prevention of radiotherapy-induced nausea and vomiting
• Prevention of postoperative nausea and vomiting (PONV)
• Supportive antiemetic therapy in cancer treatment

Dosage and Administration

• To be taken orally as directed by a physician
• Tablet should be placed on the tongue and allowed to dissolve completely
• Do not chew or swallow whole
• Dosage timing depends on treatment protocol (usually before chemotherapy or surgery)
• Use only under medical supervision

Benefits

• Rapid disintegration without need for water
• Long-lasting protection against nausea and vomiting
• Effective in both acute and delayed phases of chemotherapy-induced emesis
• Improves patient comfort and treatment compliance
• Convenient for patients with swallowing difficulty

Possible Side Effects

Common side effects may include:

• Headache
• Constipation
• Dizziness
• Fatigue
• Mild gastrointestinal discomfort

Serious reactions are rare but may include hypersensitivity or cardiac rhythm disturbances in susceptible patients.

Precautions and Warnings

• Use only under medical supervision
• Caution in patients with heart rhythm disorders or QT prolongation risk
• Inform doctor about all current medications
• Use carefully in patients with liver impairment
• Not intended for self-medication

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Storage

• Store in a cool and dry place
• Protect from moisture and light
• Keep in original packaging until use
• Keep out of reach of children

Conclusion

Paloxi ODT Tablet 0.5 mg (Palonosetron) is a convenient and effective antiemetic designed to prevent nausea and vomiting associated with chemotherapy, radiotherapy, and surgery. Its fast-dissolving formulation and long-lasting action make it a reliable option under proper medical supervision.