Palotic Injection contains Palonosetron, a second-generation serotonin (5-HT3) receptor antagonist used to prevent and treat nausea and vomiting. It is particularly effective in managing chemotherapy-induced nausea and vomiting (CINV) and post-operative nausea and vomiting (PONV). Due to its long half-life, it provides prolonged antiemetic protection with a single dose.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Palonosetron 0.075 mg per 1.5 ml solution

Indications

Palotic Injection is indicated for:

• Prevention of chemotherapy-induced nausea and vomiting (acute and delayed phases)
• Prevention and treatment of post-operative nausea and vomiting
• Nausea and vomiting associated with surgical procedures or anesthesia
• Supportive care in oncology patients receiving emetogenic therapy

Mechanism of Action

Palonosetron selectively blocks serotonin (5-HT3) receptors located in the central nervous system and gastrointestinal tract. By inhibiting serotonin binding, it prevents activation of the vomiting reflex pathway. Its strong receptor affinity and long elimination half-life provide sustained antiemetic effects.

Dosage and Administration

• Administered intravenously as a single dose prior to chemotherapy or anesthesia, or as directed by a physician.
• Must be given by a healthcare professional in a clinical or hospital setting.
• Dosage may vary depending on patient condition and treatment protocol.

Benefits

• Highly effective prevention of nausea and vomiting
• Long duration of action with single-dose administration
• Suitable for chemotherapy and surgical patients
• Improves patient comfort and treatment adherence
• Reduces need for additional antiemetic medication

Side Effects

Palotic Injection is generally well tolerated. Some possible side effects include:

• Headache
• Constipation
• Dizziness
• Fatigue
• Injection site reactions

Rare but serious reactions may occur and require medical attention.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions and Warnings

• Use only under medical supervision.
• Caution in patients with cardiac arrhythmias or prolonged QT interval.
• Dose adjustment may be required in hepatic impairment.
• Inform healthcare providers about all concurrent medications.
• Not recommended for self-administration.

Storage

• Store below 25°C
• Protect from light
• Do not freeze
• Keep out of reach of children.