Opthamox Plus Eye Drop 0.5%+0.1% is a potent combination ophthalmic solution containing Moxifloxacin Hydrochloride (0.5%) and Dexamethasone (0.1%). This dual-action formulation is designed to simultaneously treat bacterial eye infections and reduce associated inflammation, providing comprehensive relief from redness, irritation, swelling, and discomfort. Opthamox Plus Eye Drop is especially useful in cases where infection and inflammation coexist, such as bacterial conjunctivitis, postoperative ocular inflammation, or keratitis with inflammatory response.

Moxifloxacin Hydrochloride, a fourth-generation fluoroquinolone antibiotic, works by inhibiting bacterial DNA gyrase and topoisomerase IV, enzymes essential for DNA replication, transcription, and repair. This action prevents bacterial growth and leads to cell death. Dexamethasone, a potent corticosteroid, suppresses inflammation by inhibiting the release of inflammatory mediators, reducing redness, swelling, and discomfort associated with ocular infections. Together, these components provide both antimicrobial and anti-inflammatory effects in a single formulation, ensuring faster symptom relief and promoting recovery.

This combination eye drop is suitable for adults and pediatric patients (as prescribed) requiring treatment for bacterial infections with significant inflammatory response. Its ophthalmic formulation ensures direct delivery of both active agents to the affected tissues, achieving rapid therapeutic effects with minimal systemic absorption.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Key Features

• Active Ingredients: Moxifloxacin Hydrochloride 0.5% + Dexamethasone 0.1%.

• Dual Action: Combines broad-spectrum antibacterial activity with anti-inflammatory effects.

• Rapid Relief: Reduces redness, swelling, irritation, and discharge effectively.

• Targeted Ophthalmic Therapy: Direct application ensures high local drug concentration.

• Convenient Formulation: Treats infection and inflammation simultaneously.

Indications

Opthamox Plus Eye Drop 0.5%+0.1% is indicated for:

• Bacterial conjunctivitis with associated inflammation

• Keratitis with inflammatory symptoms

• Postoperative ocular inflammation following cataract or other ocular surgery

• Other ocular bacterial infections with significant inflammatory response

Treatment should follow the prescribed dosing and duration to ensure effective infection control and safe reduction of inflammation.

Mechanism of Action

• Moxifloxacin Hydrochloride: A fluoroquinolone antibiotic that inhibits bacterial DNA gyrase and topoisomerase IV, preventing bacterial DNA replication and repair, leading to bacterial cell death. Provides broad-spectrum coverage against Gram-positive and Gram-negative ocular pathogens.

• Dexamethasone: A corticosteroid that reduces inflammation by suppressing the immune response, inhibiting the release of pro-inflammatory mediators, and controlling tissue swelling, redness, and irritation.

The combination ensures that both infection and inflammation are managed efficiently, improving patient comfort and speeding recovery.

Dosage and Administration

• Instill 1–2 drops in the affected eye(s) every 4–6 hours or as directed by a physician.

• Shake the bottle well before use to ensure uniform suspension.

• Wash hands before and after administration, and avoid touching the dropper tip to the eye or any surface.

• Continue the full course as prescribed, even if symptoms improve, to prevent recurrence or resistance.

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Safety and Precautions

Opthamox Plus Eye Drop 0.5%+0.1% is generally well tolerated. Mild side effects may include temporary stinging, burning, or irritation at the application site. Prolonged use of corticosteroids may increase the risk of elevated intraocular pressure, glaucoma, or cataract formation.

• Avoid use in patients with known hypersensitivity to Moxifloxacin, Dexamethasone, or other fluoroquinolones/corticosteroids.

• Use with caution in patients with viral, fungal, or parasitic ocular infections, as corticosteroids may worsen these conditions.

• Store in a cool, dry place below 25°C, protected from sunlight, and keep out of reach of children.

Opthamox Plus Eye Drop 0.5%+0.1% offers comprehensive treatment for bacterial eye infections with inflammation, promoting rapid relief, faster recovery, and improved ocular health.