Olic Tablet 10 mg contains Obeticholic Acid, a potent farnesoid X receptor (FXR) agonist designed for the treatment of primary biliary cholangitis (PBC) in adults. PBC is a chronic autoimmune liver disease characterized by progressive damage to the bile ducts, leading to impaired bile flow, bile acid accumulation, liver inflammation, and eventual fibrosis or cirrhosis. Olic Tablet 10 mg helps regulate bile acid synthesis, reduce liver inflammation, and slow disease progression, making it a critical therapy for patients with advanced disease or insufficient response to standard treatments.

Obeticholic Acid is particularly indicated for patients who cannot tolerate or have an inadequate response to ursodeoxycholic acid (UDCA), the standard therapy for PBC. By activating FXR, Olic improves liver function, lowers harmful bile acid levels, and supports long-term liver health.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Olic Tablet 10 mg is indicated for:

• Primary Biliary Cholangitis (PBC) in adult patients

• Patients with inadequate response or intolerance to UDCA

• Reduction of liver inflammation and bile acid accumulation in chronic cholestatic liver disease

• Slowing the progression of fibrosis and maintaining liver function

Mechanism of Action

Obeticholic Acid works through farnesoid X receptor (FXR) activation:

1. Regulation of Bile Acid Synthesis: FXR activation reduces the production of bile acids in the liver, preventing accumulation and toxicity.

2. Hepatoprotective Effect: Minimizes hepatocyte damage caused by toxic bile acids.

3. Anti-inflammatory Action: Modulates inflammatory pathways to reduce liver inflammation and injury.

4. Improvement of Liver Biochemistry: Reduces elevated liver enzymes, particularly alkaline phosphatase (ALP) and bilirubin, which are markers of PBC activity.

By addressing both the cause and consequences of bile acid buildup, Olic 10 mg supports liver function and slows disease progression.

Dosage and Administration

• Recommended dose: Usually 10 mg once daily, orally, as prescribed by a physician.

• Tablets may be taken with or without food, preferably at the same time each day.

• Dose adjustments may be required based on liver function and patient tolerance.

• Regular monitoring of liver enzymes is advised to evaluate therapeutic response and safety.

Precautions and Warnings

• Use caution in patients with severe liver impairment or cirrhosis.

• Monitor for pruritus (itching), a common side effect of FXR agonists.

• Not recommended during pregnancy or breastfeeding unless advised by a healthcare professional.

• Avoid combining with other bile acid-lowering medications without physician guidance.

• Dose modifications may be necessary in patients with moderate to severe hepatic dysfunction.

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Possible Side Effects

Olic Tablet 10 mg is generally well-tolerated. Common side effects include:

• Pruritus (itching)

• Fatigue or weakness

• Abdominal discomfort

• Mild nausea

Rare but serious adverse effects may include worsening liver function or cholestasis. Patients should seek immediate medical attention if severe symptoms occur.

Storage

Store below 30°C in a dry, cool place, protected from light and moisture. Keep out of reach of children.

Olic Tablet 10 mg offers targeted therapy for primary biliary cholangitis, providing effective bile acid regulation, reducing liver inflammation, and supporting long-term liver health in patients requiring enhanced or alternative treatment to standard therapy.