Nifev Capsule 100 mg contains Nintedanib, a targeted therapy used to manage idiopathic pulmonary fibrosis (IPF) and other progressive fibrosing interstitial lung diseases. Nintedanib is an anti-fibrotic and tyrosine kinase inhibitor that helps slow disease progression by reducing lung tissue scarring and improving respiratory function.

Pulmonary fibrosis is a chronic condition characterized by stiffening and scarring of lung tissue, leading to shortness of breath, reduced exercise tolerance, and declining lung function. Nifev 100 mg is designed to help patients maintain lung capacity and slow the progression of the disease, improving quality of life and long-term outcomes.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

Each capsule contains:

• Nintedanib 100 mg

Mechanism of Action

Nintedanib is a tyrosine kinase inhibitor that targets multiple growth factor receptors involved in fibrosis, including:

• Platelet-derived growth factor receptor (PDGFR)

• Fibroblast growth factor receptor (FGFR)

• Vascular endothelial growth factor receptor (VEGFR)

By inhibiting these receptors, Nifev 100 mg reduces the proliferation and activation of fibroblasts, the cells responsible for collagen deposition and lung tissue scarring. This slows the fibrotic process and preserves lung function over time.

Key effects include:

• Slowing disease progression in IPF and other fibrosing lung diseases

• Reducing inflammation and fibroblast activity in lung tissue

• Supporting better respiratory function and exercise tolerance

Indications

Nifev Capsule 100 mg is indicated for:

• Idiopathic pulmonary fibrosis (IPF)

• Progressive fibrosing interstitial lung diseases

• Patients at risk of rapid lung function decline due to fibrosis

It is prescribed under specialist supervision and is not a cure but helps manage disease progression and symptoms.

Dosage and Administration

The usual starting dose of Nifev Capsule 100 mg is determined by a healthcare professional, typically administered twice daily with food. Capsules should be swallowed whole with water and not chewed or crushed.

Dosage adjustments may be necessary in patients with liver impairment or in those experiencing side effects. Regular monitoring of liver function and blood parameters is recommended during treatment to ensure safety.

Benefits

• Slows the progression of pulmonary fibrosis

• Reduces fibroblast activity and tissue scarring in the lungs

• Helps maintain lung function and respiratory capacity

• Improves exercise tolerance and quality of life

• Targeted therapy with a specific mechanism for fibrotic diseases

Possible Side Effects

Nifev Capsule 100 mg is generally well-tolerated, but side effects may include:

• Diarrhea

• Nausea or vomiting

• Liver enzyme elevation

• Abdominal pain or discomfort

• Fatigue or weakness

Serious side effects are rare but may include severe liver injury, bleeding, or gastrointestinal perforation. Patients should contact their healthcare provider if they experience persistent diarrhea, jaundice, or unexplained bruising.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions and Warnings

• Use cautiously in patients with liver impairment, cardiovascular disease, or gastrointestinal disorders.

• Regular monitoring of liver function tests is recommended during therapy.

• Not recommended during pregnancy or breastfeeding. Effective contraception is advised for women of childbearing potential.

• Inform your physician about all medications being taken to avoid drug interactions.

Storage

Store below 30°C in a dry place, protected from light and moisture. Keep out of reach of children.

Nifev Capsule 100 mg provides targeted anti-fibrotic therapy for managing idiopathic pulmonary fibrosis and progressive fibrosing lung diseases, helping slow disease progression and maintain lung health under specialist supervision.